Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 5/20 | 0.34 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TNKS | O95271 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL8166220 | 0.83 | ADRA1D (0.42) | ADRA1DADRA1AADRA1BLMNATSHR | |
| SCHEMBL8175103 | 0.82 | TRPC3 (0.49) | ADRA1DADRA1AADRA1BSMN1; SMN2FAAH | |
| SCHEMBL8166794 | 0.78 | ADRA1D (0.57) | ADRA1DADRA1AADRA1BLMNATSHR | |
| SCHEMBL8178641 | 0.77 | ADRA1D (0.49) | ADRA1DADRA1AADRA1BLMNAHCRTR2 | |
| SCHEMBL8166964 | 0.74 | ADRA1D (0.59) | ADRA1DADRA1AADRA1BLMNATSHR | |
| SCHEMBL8173521 | 0.72 | ADRA1D (0.53) | ADRA1DADRA1AADRA1BTSHRMEN1 | |
| SCHEMBL8174451 | 0.72 | ADRA1D (0.52) | ADRA1DADRA1AADRA1B | |
| SCHEMBL8180362 | 0.71 | ADRA1D (0.44) | ADRA1DADRA1AADRA1BMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8174041 | 0.71 | ADRA1D (0.87) | ADRA1DADRA1AADRA1BTSHRSSTR5 | |
| Hydrochloric Acid SCHEMBL8173485 | 0.71 | ADRA1D (0.51) | ADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6090825-A | Oxazole derivatives as antagonists of alpha 1C andrenergic receptors | GLAXO WELLCOME INC. (US) | 2000-07-18 | — | — | US | disclosed |