Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 9/20 | 0.42 |
| ▸ | FABP7 | O15540 | 2/20 | 0.41 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.41 |
| ▸ | FFAR2 | O15552 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21553619 | 0.93 | AGTR2 (0.48) | AGTR2FABP7FABP5MMP9KMT2A | |
| SCHEMBL16095440 | 0.93 | AGTR2 (0.48) | AGTR2FABP7FABP5MMP9KMT2A | |
| SCHEMBL21874030 | 0.93 | AGTR2 (0.48) | AGTR2FABP7FABP5MMP9KMT2A | |
| SCHEMBL31210291 | 0.93 | AGTR2 (0.48) | AGTR2FABP7FABP5MMP9KMT2A | |
| SCHEMBL5963754 | 0.93 | AGTR2 (0.48) | AGTR2FABP7FABP5MMP9KMT2A | |
| SCHEMBL12649496 | 0.89 | AGTR2 (0.41) | AGTR2FABP7FABP5L3MBTL1KMT2A | |
| SCHEMBL16277190 | 0.86 | FFAR2 (0.45) | AGTR2FFAR2L3MBTL1S1PR5 | |
| SCHEMBL25358048 | 0.86 | FABP5 (0.42) | AGTR2FABP7FABP5FFAR2L3MBTL1 | |
| SCHEMBL29400879 | 0.85 | AGTR2 (0.43) | AGTR2FABP7FABP5KMT2A | |
| SCHEMBL31080808 | 0.84 | FABP5 (0.42) | AGTR2FABP7FABP5ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2279777-A2 | Compounds and compositions as channel activating protease inhibitors | IRM LLC (BM) | 2011-02-02 | — | — | EP | disclosed |
| US-20080176901-A1 | COMPOUNDS AND COMPOSITIONS AS CHANNEL ACTIVATING PROTEASE INHIBITORS | IRM LLC (BM) | 2008-07-24 | — | — | US | disclosed |
| US-20080176901-A1 | COMPOUNDS AND COMPOSITIONS AS CHANNEL ACTIVATING PROTEASE INHIBITORS | IRM LLC (BM) | 2008-07-24 | — | — | US | disclosed |
| WO-2008085608-A1 | COMPOUNDS AND COMPOSITIONS AS CHANNEL ACTIVATING PROTEASE INHIBITORS | IRM LLC (BM) | 2008-07-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080176901-A1 | COMPOUNDS AND COMPOSITIONS AS CHANNEL ACTIVATING PROTEASE INHIBITORS | PRSS1, PRSS8, PRSS2 | AGTR2 1121/4885FABP7 2571/4885FABP5 3356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.