Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | HCAR2 | Q8TDS4 | 7/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 5/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8166653 | 1.00 | ATM (0.48) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL7645953 | 0.79 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL16648784 | 0.79 | THRB (0.30) | — | |
| SCHEMBL9067562 | 0.78 | ATM (0.39) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL27943807 | 0.77 | — | — | |
| SCHEMBL7645955 | 0.77 | — | — | |
| SCHEMBL15066950 | 0.76 | — | — | |
| SCHEMBL12284482 | 0.76 | ADRA2A (0.46) | MAPTTSHRCYP3A4 | |
| SCHEMBL11576466 | 0.74 | CHRNB2 (0.31) | — | |
| SCHEMBL28041775 | 0.74 | CYP1A2 (0.33) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6034199-A | USING ACETYLENIC DIESTER AS POLYMERIZATION INHIBITOR | GENERAL ELECTRIC COMPANY (US) | 2000-03-07 | — | — | US | disclosed |
| US-6015853-A | STABILIZING POLYSILOXANE WITH ACETYLENIC MALEATE DERIVATIVE | GENERAL ELECTRIC COMPANY (US) | 2000-01-18 | — | — | US | disclosed |
| US-6002039-A | Liquid injection molding inhibitors for curable compositions | GENERAL ELECTRIC COMPANY (US) | 1999-12-14 | — | — | US | disclosed |
| US-5948339-A | Method of producing articles using new liquid injection molding inhibitors for curable compositions | GENERAL ELECTRIC COMPANY (US) | 1999-09-07 | — | — | US | disclosed |
| US-5928564-A | Liquid injection molding inhibitors for curable compositions | GENERAL ELECTRIC COMPANY (US) | 1999-07-27 | — | — | US | disclosed |
| US-5922795-A | Liquid injection molding inhibitors for curable compositions | GENERAL ELECTRIC COMPANY (US) | 1999-07-13 | — | — | US | disclosed |
| US-5506289-A | ACETYLENIC MALEATES AND FUMARATES AND DERIVATIVES AS POLYSILOXANE CURING INHIBITORS, CREATING NEW COMPOSITIONS OF HIGH HARDNESS AND TEAR STRENGTH | MOMENTIVE PERFORMANCE MATERIALS INC. | 1996-04-09 | — | — | US | disclosed |