Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 3/20 | 0.50 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NT5E | P21589 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | PNP | P00491 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8165796 | 0.89 | HSP90AA1 (0.40) | AHCYLMNANT5EPNPTP53 | |
| SCHEMBL8171715 | 0.85 | ADORA3 (0.51) | AHCYTP53SMN1; SMN2ADORA2AADORA3 | |
| SCHEMBL8469441 | 0.81 | AHCY (0.52) | AHCYHSP90B1LMNANT5EHIF1A | |
| SCHEMBL9035660 | 0.81 | AHCY (0.52) | AHCYHSP90B1LMNANT5EHIF1A | |
| SCHEMBL8169026 | 0.81 | ADORA3 (0.48) | PNPPDE3AADORA3 | |
| SCHEMBL8088533 | 0.77 | AHCY (0.50) | AHCYHSP90B1LMNANT5EHIF1A | |
| SCHEMBL3239663 | 0.74 | LMNA (0.59) | AHCYHSP90B1LMNANT5EHIF1A | |
| SCHEMBL9114703 | 0.74 | AHCY (0.54) | AHCYHSP90B1LMNANT5EHIF1A | |
| SCHEMBL9114712 | 0.74 | AHCY (0.54) | AHCYHSP90B1LMNANT5EHIF1A | |
| SCHEMBL25712959 | 0.74 | LMNA (0.59) | AHCYHSP90B1LMNANT5EHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3047045-B2 | — | — | 2000-05-29 | — | — | JP | claimed |
| EP-0869953-A1 | NUCLEOSIDE DERIVATIVES AND PROCESS FOR PREPARING THEREOF | CHONG KUN DANG CORP (KR) | 1998-10-14 | — | — | EP | claimed |
| WO-1996012716-A1 | NUCLEOSIDE DERIVATIVES AND PROCESS FOR PREPARING THEREOF | CHONG KUN DANG CORP. (KR) | 1996-05-02 | — | — | WO | claimed |