Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | SCN1A | P35498 | 1/20 | 0.50 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.50 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8167085 | 0.94 | EPHX2 (0.51) | LMNANPC1RAB9AEPHX2SMN1; SMN2 | |
| SCHEMBL27666301 | 0.84 | TAS1R3 (0.55) | LMNACYP1A2CYP2D6SCN1ASCN2A | |
| SCHEMBL27666303 | 0.84 | TAS1R3 (0.55) | LMNACYP1A2CYP2D6SCN1ASCN2A | |
| SCHEMBL15989223 | 0.81 | METAP2 (0.48) | LMNACYP1A2CYP2D6SCN1ASCN2A | |
| SCHEMBL8174021 | 0.79 | MEN1 (0.53) | LMNACYP1A2NPC1RAB9AEPHX2 | |
| SCHEMBL20583729 | 0.78 | RAB9A (0.46) | NPC1RAB9ASMN1; SMN2CYP2C9MEN1 | |
| SCHEMBL5394237 | 0.78 | PTGS2 (0.67) | LMNANPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL10719116 | 0.78 | LMNA (0.46) | LMNACYP1A2CYP2D6SCN1ASCN2A | |
| SCHEMBL8173186 | 0.77 | POLB (0.50) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL6639389 | 0.77 | RAB9A (0.61) | CYP1A2NPC1RAB9AEPHX2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6013836-A | PARTICULARLY ACTIVE AGAINST MOTHS AND BEETLES AND THEIR INSECT GROWTH REGULATING ACTIVITY WITHOUT ADVERSE IMPACT ON BENEFICIAL INSECTS; CROPS; FORESTRY | ROHM AND HAAS COMPANY (US) | 2000-01-11 | — | — | US | disclosed |