Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | PTPRF | P10586 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8175916 | 0.91 | EGFR (0.46) | CA1CA2MAPTNPC1PTPRC | |
| SCHEMBL8167327 | 0.90 | TDP1 (0.46) | MAPTNPC1PTPRCPTPRFPTPN1 | |
| SCHEMBL8180152 | 0.90 | CA1 (0.46) | CA1CA2LMNAPTPRCPTPRF | |
| SCHEMBL7922803 | 0.90 | CA1 (0.46) | CA1CA2MAPTNPC1KMT2A | |
| SCHEMBL8176971 | 0.89 | MAPT (0.43) | MAPTNPC1LMNAKMT2AMEN1 | |
| SCHEMBL8166934 | 0.89 | SLC6A4 (0.48) | MAPTNPC1LMNAPTPRCPTPRF | |
| SCHEMBL8175487 | 0.89 | EGFR (0.40) | CA1CA2MAPTKMT2AMEN1 | |
| SCHEMBL8175144 | 0.89 | SLC6A4 (0.48) | MAPTNPC1KMT2AMEN1PTPRC | |
| SCHEMBL8175906 | 0.89 | MAPT (0.47) | MAPTNPC1KMT2AMEN1HDAC8 | |
| SCHEMBL8167132 | 0.88 | RAB9A (0.44) | CA1CA2MAPTNPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6150413-A | TREATMENT OF DERMATOLOGICAL, RHEUMATIC, RESPIRATORY, CARDIOVASCULAR, BONE AND OPHTHALMOLOGICAL DISORDERS, AS WELL AS MAMMALIAN SKIN AND HAIR CONDITIONS; 4-(4-(BIPHENYL-2-YL)BUT-3-EN-1-YNYL)BENZOIC ACID, FOR EXAMPLE | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (FR) | 2000-11-21 | — | — | US | disclosed |