Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.34 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4854314 | 0.82 | SLC6A2 (0.37) | SLC6A2HTR2ASLC6A4HRH1OPRD1 | |
| SCHEMBL22173410 | 0.78 | — | — | |
| SCHEMBL15821175 | 0.78 | HTR7 (0.38) | HTR7PLA2G7HTR1ANPC1CASP3 | |
| SCHEMBL6912627 | 0.77 | PRCP (0.40) | HTR7HTR1ANISCHALDH1A1PARP10 | |
| SCHEMBL6930009 | 0.76 | HTR7 (0.39) | HTR7HTR1ASLC6A2HTR2ASLC6A4 | |
| SCHEMBL29767585 | 0.76 | HTR7 (0.39) | HTR7HTR1ASLC6A2HTR2ASLC6A4 | |
| SCHEMBL693026 | 0.76 | PRCP (0.34) | HTR7HTR1ASLC6A2HTR2ASLC6A4 | |
| SCHEMBL28316529 | 0.75 | BRD4 (0.34) | HTR1AACHEMEN1KMT2ABRD4 | |
| SCHEMBL28134294 | 0.74 | HSD11B1 (0.37) | HTR2ACYP1A2ALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL5344329 | 0.70 | HTR7 (0.38) | HTR7PLA2G7HTR1AHTR2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3710491-B1 | (DI)SILICON BRIDGED METALLOCENES THAT PRODUCE POLYETHYLENE BROAD MOLECULAR WEIGHT DISTRIBUTION AND MOLECULAR WEIGHT | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2025-01-01 | — | — | EP | disclosed |
| CN-111372954-B | Preparation of polyethylene (bis) silicon-bridged metallocenes with broad molecular weight distribution and molecular weight | 埃克森美孚化学专利公司 | 2022-06-28 | — | — | CN | disclosed |
| US-11214631-B2 | (Di)silicon bridged metallocenes that produce polyethylene with broad molecular weight distribution and high molecular weight | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2022-01-04 | — | — | US | disclosed |
| EP-3710491-A1 | (DI)SILICON BRIDGED METALLOCENES THAT PRODUCE POLYETHYLENE BROAD MOLECULAR WEIGHT DISTRIBUTION AND MOLECULAR WEIGHT | ExxonMobil Chemical Patents Inc. (US) | 2020-09-23 | — | — | EP | disclosed |
| CN-111372954-A | Preparation of polyethylene (bis) silicon-bridged metallocenes with broad molecular weight distribution and molecular weight | 埃克森美孚化学专利公司 | 2020-07-03 | — | — | CN | disclosed |
| US-20190144571-A1 | (Di)Silicon Bridged Metallocenes that Produce Polyethylene with Broad Molecular Weight Distribution and High Molecular Weight | EXXONMOBIL CHEMICAL PATENTS INC. | 2019-05-16 | — | — | US | disclosed |
| EP-0968158-A1 | METHOD OF PREPARING SUBSTITUTED INDANONES, THE SUBSTITUTED INDANONES AND METALLOCENES PREPARED THEREFROM | Basell Polyolefine GmbH (DE) | 2000-01-05 | — | — | EP | disclosed |
| WO-1998040331-A1 | PREPARATION OF PREPARING SUBSTITUTED INDANONES | TARGOR GMBH (DE) | 1998-09-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190144571-A1 | (Di)Silicon Bridged Metallocenes that Produce Polyethylene with Broad Molecular Weight Distribution and High Molecular Weight | MDM4, MAL2, MSI2 | HTR7 2740/4885PLA2G7 3163/4885HTR1A 2408/4885 |
| US-11214631-B2 | (Di)silicon bridged metallocenes that produce polyethylene with broad molecular weight distribution and high molecular weight | MDM4, MAL2, MSI2 | HTR7 2740/4885PLA2G7 3163/4885HTR1A 2408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.