Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | DPP4 | P27487 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.37 |
| ▸ | IDH1 | O75874 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10059392 | 0.74 | ALDH1A1 (0.49) | HPGDALDH1A1KDM4ETDP1MAPT | |
| SCHEMBL16897065 | 0.71 | MAOA (0.41) | MAOADPP4HPGDALDH1A1KDM4E | |
| SCHEMBL16113539 | 0.68 | GLO1 (0.60) | MAOAL3MBTL1IDH1ERCC1FEN1 | |
| SCHEMBL8161615 | 0.66 | FEN1 (0.48) | HPGDALDH1A1KDM4ETDP1MAPT | |
| SCHEMBL3159532 | 0.64 | MAOA (0.41) | MAOAHPGDALDH1A1KDM4ETDP1 | |
| SCHEMBL5649590 | 0.64 | HPGD (0.50) | MAOADPP4HPGDALDH1A1KDM4E | |
| SCHEMBL10586275 | 0.64 | ALDH1A1 (0.47) | MAOAHPGDALDH1A1KDM4ETDP1 | |
| SCHEMBL3545 | 0.64 | L3MBTL1 (0.57) | DPP4HPGDALDH1A1KDM4ETDP1 | |
| SCHEMBL16291133 | 0.64 | L3MBTL1 (0.57) | DPP4HPGDALDH1A1KDM4ETDP1 | |
| SCHEMBL9198888 | 0.63 | KDM4E (0.46) | HPGDALDH1A1KDM4ETDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000067699-A2 | PHARMACEUTICAL COMPOSITIONS FOR TREATING MALARIA | ARCH CHEMICALS, INC. (US) | 2000-11-16 | — | — | WO | claimed |
| US-5675013-A | SHAMPOO AND SKIN PRODUCTS; PAINTS, COATINGS, SEALS, SOAPS, ADHESIVES, ELASTOMERS AND COSMETICS; RECEPTIVITY; WATER AND SOLVENT SOLUBILITY; NONHYDROLYZING AND NONDESTRUCTIVE | OLIN CORPORATION (US) | 1997-10-07 | — | — | US | disclosed |
| US-5424435-A | Microbiocides | OLIN CORPORATION (US) | 1995-06-13 | — | — | US | disclosed |