Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 4/20 | 0.33 |
| ▸ | GLS | O94925 | 2/20 | 0.33 |
| ▸ | FBP1 | P09467 | 9/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.30 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8177319 | 0.93 | ITGB3 (0.36) | F2GLSFBP1ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL8222330 | 0.92 | ITGB3 (0.36) | F2GLSFBP1ITGB3ITGA2B | |
| SCHEMBL8168501 | 0.85 | ITGB3 (0.42) | ITGB3ITGA2B | |
| SCHEMBL8210927 | 0.83 | F2 (0.40) | F2GLSFBP1MEN1CYP3A4 | |
| SCHEMBL8210925 | 0.83 | F2 (0.40) | F2GLSFBP1MEN1CYP3A4 | |
| SCHEMBL8216119 | 0.82 | ITGB3 (0.39) | F2GLSITGB3ITGA2B | |
| SCHEMBL7367606 | 0.80 | SLC1A3 (0.36) | F2GLSFBP1 | |
| SCHEMBL8176184 | 0.80 | GLS (0.37) | F2GLSFBP1MEN1CYP3A4 | |
| SCHEMBL8176181 | 0.80 | GLS (0.37) | F2GLSFBP1MEN1CYP3A4 | |
| SCHEMBL8177325 | 0.74 | ITGB3 (0.46) | F2ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153628-A | 1,3,4-thiadiazoles and 1,3,4-Oxadiazoles as αv β3 antagonists | DUPONT PHARMACEUTICALS COMPANY (US) | 2000-11-28 | — | — | US | disclosed |