Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 16/20 | 1.00 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.74 |
| ▸ | NQO2 | P16083 | 3/20 | 0.74 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | HTR2C | P28335 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7016566 | 0.88 | MTNR1A (0.91) | MTNR1AMTNR1BNQO2HTR2C | |
| SCHEMBL7018941 | 0.85 | MTNR1A (1.00) | MTNR1AMTNR1BNQO2HTR2C | |
| SCHEMBL8169111 | 0.84 | MTNR1A (0.80) | MTNR1AMTNR1BNQO2HTR2C | |
| SCHEMBL6217496 | 0.82 | MTNR1A (0.72) | MTNR1AMTNR1BNQO2TSHRHTR2C | |
| SCHEMBL5346051 | 0.81 | MTNR1A (0.74) | MTNR1AMTNR1BNQO2TSHR | |
| SCHEMBL7022717 | 0.81 | MTNR1A (0.70) | MTNR1AMTNR1BNQO2HTR2C | |
| SCHEMBL7019235 | 0.81 | MTNR1A (0.94) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL7014411 | 0.80 | MTNR1A (1.00) | MTNR1AMTNR1B | |
| SCHEMBL5337710 | 0.79 | MTNR1B (0.79) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL5344150 | 0.79 | NQO2 (0.72) | MTNR1AMTNR1BNQO2HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6071946-A | FOR TREATING DISORDERS OF THE MELATONINERGIC SYSTEM, SLEEP DISORDERS, CIRCADIAN RHYTHM DISORDERS | ADIR ET COMPAGNIE (FR) | 2000-06-06 | — | — | US | disclosed |
| US-5998461-A | SLEEP DISORDERS | ADIR ET COMPAGNIE (FR) | 1999-12-07 | — | — | US | disclosed |