Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNPAT | O15228 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 2/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | MMP14 | P50281 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 3/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | QRFPR | Q96P65 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8169814 | 0.88 | MMP1 (0.53) | GNPATMMP8MMP9MMP1MMP3 | |
| SCHEMBL8169810 | 0.88 | MMP1 (0.53) | GNPATMMP8MMP9MMP1MMP3 | |
| SCHEMBL20653766 | 0.85 | MMP9 (0.51) | GNPATMMP8MMP9MMP14MMP1 | |
| SCHEMBL8164939 | 0.83 | MMP9 (0.46) | MMP8MMP9CTSSFOLH1 | |
| SCHEMBL8164942 | 0.83 | MMP9 (0.46) | MMP8MMP9CTSSFOLH1 | |
| SCHEMBL8164922 | 0.83 | MMP9 (0.46) | MMP8MMP9CTSSFOLH1 | |
| SCHEMBL8173933 | 0.80 | REN (0.47) | MMP8MMP9MMP14MMP1MMP3 | |
| SCHEMBL8173837 | 0.80 | REN (0.47) | MMP8MMP9MMP14MMP1MMP3 | |
| SCHEMBL6319141 | 0.77 | MMP9 (0.66) | MMP8MMP9MMP14MMP3 | |
| SCHEMBL7064976 | 0.77 | MMP9 (0.66) | MMP8MMP9MMP14MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127341-A | AMINOMETHYL-N-(1-((2-(2-THIENYL)-1-(1-CARBAMOYL-5 -AMINOPENTYLCARBAMOYL)ETHYL)-N-METHYLCARBAMOYL)-2-(2 -NAPTHYL)ETHYL)BENZAMIDE, FOR EXAMPLE; ADMINISTERING TO STIMULATE GROWTH, MILK OR WOOL PRODUCTION IN ANIMALS | NOVO NORDISK A/S (DK) | 2000-10-03 | — | — | US | disclosed |
| EP-1005484-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 2000-06-07 | — | — | EP | disclosed |
| WO-1998058950-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1998-12-30 | — | — | WO | disclosed |