Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.37 |
| ▸ | GRIA3 | P42263 | 3/20 | 0.37 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7948487 | 0.84 | HSD17B10 (0.44) | HSD17B10GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL8634867 | 0.74 | GRIN2D (0.44) | HSD17B10GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL7521972 | 0.71 | KDM4E (0.53) | HSD17B10GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL5544512 | 0.70 | ADH1B (0.48) | ALDH1A1TAAR1ADH1BADH1CADH1A | |
| SCHEMBL7957683 | 0.70 | GRIN2D (0.50) | HSD17B10GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL8037105 | 0.70 | CFB (0.48) | HSD17B10GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL20334459 | 0.69 | EZH2 (0.43) | KDM4E | |
| SCHEMBL8040463 | 0.69 | CFB (0.50) | HSD17B10KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL8037118 | 0.69 | CFB (0.50) | HSD17B10KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL8037080 | 0.68 | HSD17B10 (0.38) | HSD17B10GRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6063774-A | NERVOUS SYSTEM DISORDERS | WARNER-LAMBERT COMPANY (US) | 2000-05-16 | — | — | US | disclosed |