Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 5/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.46 |
| ▸ | MRGPRX1 | Q96LB2 | 3/20 | 0.44 |
| ▸ | PLAU | P00749 | 2/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 4/20 | 0.41 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 4/20 | 0.39 |
| ▸ | F7 | P08709 | 2/20 | 0.39 |
| ▸ | F12 | P00748 | 1/20 | 0.39 |
| ▸ | F3 | P13726 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8174776 | 0.77 | PLAU (0.44) | PRSS1PRSS2PRSS3PLAUF10 | |
| SCHEMBL8174902 | 0.75 | PRSS1 (0.36) | PRSS1PRSS2PRSS3PLAULOXL2 | |
| SCHEMBL8173364 | 0.73 | PRSS1 (0.43) | PRSS1PRSS2PRSS3F2 | |
| SCHEMBL4599833 | 0.73 | LMNA (0.45) | — | |
| SCHEMBL4599182 | 0.73 | HTT (0.43) | — | |
| SCHEMBL4603282 | 0.73 | PKM (0.42) | PKM | |
| SCHEMBL8173655 | 0.73 | PLAU (0.55) | PRSS1PRSS2PRSS3PLAULOXL2 | |
| SCHEMBL7329993 | 0.71 | MRGPRX1 (0.74) | PRSS1PRSS2PRSS3MRGPRX1F10 | |
| SCHEMBL693665 | 0.70 | HSD17B10 (0.47) | — | |
| SCHEMBL3285826 | 0.70 | APP (0.44) | BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114328-A | ANTICOAGULANTS; BLOOD DISORDERS | DUPONT PHARMACEUTICALS COMPANY (US) | 2000-09-05 | — | — | US | disclosed |