Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 14/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8170639 | 0.80 | PLAU (0.38) | PRSS1PLAUPRSS2PRSS3LOXL2 | |
| SCHEMBL8173364 | 0.78 | PRSS1 (0.43) | PRSS1PRSS2PRSS3 | |
| SCHEMBL8169762 | 0.75 | PRSS1 (0.46) | PRSS1PLAUPRSS2PRSS3LOXL2 | |
| SCHEMBL1664327 | 0.74 | ESR1 (0.35) | — | |
| SCHEMBL8170185 | 0.73 | PLAU (0.38) | PRSS1PLAUPRSS2PRSS3LOXL2 | |
| SCHEMBL8174776 | 0.69 | PLAU (0.44) | PRSS1PLAUPRSS2PRSS3 | |
| SCHEMBL1950632 | 0.68 | PRSS1 (0.50) | PRSS1PLAUPRSS2PRSS3LOXL2 | |
| SCHEMBL7985427 | 0.67 | PRSS1 (0.41) | PRSS1PLAUPRSS2PRSS3LOXL2 | |
| SCHEMBL8169486 | 0.67 | PRSS1 (0.39) | PRSS1PLAUPRSS2PRSS3 | |
| SCHEMBL1666989 | 0.66 | IDO1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114328-A | ANTICOAGULANTS; BLOOD DISORDERS | DUPONT PHARMACEUTICALS COMPANY (US) | 2000-09-05 | — | — | US | disclosed |