SCHEMBL817016

SCHEMBL817016

CCc1cc(N)c(Cl)c(CC)c1Cc1c(CC)cc(N)c(Cl)c1CC

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DHFR P00374 1/20 0.36
MAP4K1 Q92918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3678947 0.86 ALDH1A1 (0.34) DHFR
SCHEMBL1825933 0.84 DHFR (0.36) DHFRMAP4K1
SCHEMBL17203755 0.83 DHFR (0.34) DHFRMAP4K1
SCHEMBL25765759 0.74 DHFR (0.33) DHFR
SCHEMBL10342242 0.72 DHFR (0.39) DHFRMAP4K1
SCHEMBL3686293 0.72 CSNK2A2 (0.33) DHFR
SCHEMBL3678945 0.72 DHFR (0.36) DHFR
SCHEMBL28319291 0.72 SMN1; SMN2 (0.31) DHFR
SCHEMBL394710 0.72 NOS3 (0.39) DHFRMAP4K1
SCHEMBL11230051 0.71 CYP3A4 (0.35) DHFRMAP4K1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 325 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240198183-A1 GOLF BALLS HAVING UNIQUE EFFECT PIGMENTS IN ONE OR MORE LAYERS JPMORGAN CHASE BANK, N.A. 2024-06-20 US disclosed
US-20240198185-A1 GOLF BALL INCORPORATING INORGANIC ALUMINOSILICATE CERAMIC MICROSPHERES IN AT LEAST ONE LAYER ACUSHNET COMPANY (US) 2024-06-20 US disclosed
US-20240198182-A1 GOLF BALLS HAVING CHROMOGENIC POLYMERS IN ONE OR MORE LAYERS JPMORGAN CHASE BANK, N.A. 2024-06-20 US disclosed
US-20240198184-A1 WHITE GOLF BALL ACUSHNET COMPANY (US) 2024-06-20 US disclosed
US-12005319-B1 Golf ball components formed from hydroxyurethane compositions ACUSHNET COMPANY (US) 2024-06-11 US disclosed
US-11969925-B2 Injection molding method and mold ACUSHNET COMPANY (US) 2024-04-30 US disclosed
US-20240100399-A1 METHODS FOR APPLYING POLYURETHANE COATINGS TO GOLF BALLS HAVING A THERMOPLASTIC POLYURETHANE COVER ACUSHNET COMPANY (US) 2024-03-28 US disclosed
US-20240091596-A1 GOLF BALL AND METHOD OF MAKING SAME ACUSHNET COMPANY (US) 2024-03-21 US disclosed
US-11918861-B2 Golf ball incorporating functionalized inorganic aluminosilicate ceramic microspheres in at least one core layer ACUSHNET COMPANY (US) 2024-03-05 US disclosed
US-11919723-B2 System and method for automatedly detecting and rejecting cores having a non-conforming core color prior to covering Milbank, Mandi B. (US) 2024-03-05 US disclosed
US-20050004325-A1 Compositions for golf equipment JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-01-06 US disclosed
US-20040266558-A1 Interpenetrating polymer networks using blocked polyurethane/polyurea prepolymers for golf ball layers JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-12-30 US disclosed
US-20040220356-A1 Compositions for golf equipment JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-11-04 US disclosed
US-20040220378-A1 Compositions for golf equipment JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-11-04 US disclosed
US-20040220377-A1 Compositions for golf equipment JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-11-04 US disclosed
US-20040220373-A1 Compositions for golf equipment JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-11-04 US disclosed
US-20040220357-A1 Compositions for golf equipment JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-11-04 US disclosed
US-20040220371-A1 Compositions for golf equipment JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-11-04 US disclosed
US-20040220375-A1 Compositions for golf equipment JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-11-04 US disclosed
US-20040198940-A1 Golf ball cover compositions JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-10-07 US disclosed