Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.30 |
| ▸ | GABRP | O00591 | 1/20 | 0.30 |
| ▸ | GABRD | O14764 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.30 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.30 |
| ▸ | GABRE | P78334 | 1/20 | 0.30 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.30 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.30 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.30 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL817016 | 0.84 | DHFR (0.36) | DHFRMAP4K1 | |
| SCHEMBL17203755 | 0.79 | DHFR (0.34) | DHFRMAP4K1 | |
| SCHEMBL394710 | 0.76 | NOS3 (0.39) | DHFRMAP4K1GABRPGABRDGABRA1 | |
| SCHEMBL11230051 | 0.75 | CYP3A4 (0.35) | DHFRTAAR1MAP4K1 | |
| SCHEMBL9799254 | 0.74 | POLB (0.38) | DHFRMAP4K1 | |
| SCHEMBL3678947 | 0.73 | ALDH1A1 (0.34) | DHFR | |
| SCHEMBL10342242 | 0.72 | DHFR (0.39) | DHFRMAP4K1 | |
| SCHEMBL3678945 | 0.72 | DHFR (0.36) | DHFR | |
| SCHEMBL28319291 | 0.72 | SMN1; SMN2 (0.31) | DHFR | |
| SCHEMBL11800708 | 0.71 | CTRC (0.36) | MAP4K1GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6949589-B2 | Elastic foamed grinder material and method for producing the same | OYAIZU YOSHIJIRO | 2005-09-27 | — | — | US | claimed |
| US-20030066245-A1 | Elastic foamed grinder material and method for producing the same | OYAIZU YOSHIJIRO (JP) | 2003-04-10 | — | — | US | claimed |
| US-10280333-B2 | Coating compositions | Seagrave Coatings Corp. (US) | 2019-05-07 | — | — | US | disclosed |
| EP-3061622-A1 | COATING COMPOSITIONS | Seagrave Coating Corp. (US) | 2016-08-31 | — | — | EP | disclosed |
| US-20160237309-A1 | SOLVENT-FREE POLYURETHANE 100% SOLIDS COATING | SEAGRAVE COATINGS | 2016-08-18 | — | — | US | disclosed |
| EP-2318450-B1 | NOVEL CURING AGENTS AND PROCESS FOR THEIR MANUFACTURE | HEXCEL COMPOSITES LTD (GB) | 2014-02-26 | — | — | EP | disclosed |
| US-8461275-B2 | Curing agents and process for their manufacture | Hexcal Composites Limited (GB) | 2013-06-11 | — | — | US | disclosed |
| US-20110130525-A1 | NOVEL CURING AGENTS AND PROCESS FOR THEIR MANUFACTURE | Hexcel Corporation Ltd (GB) | 2011-06-02 | — | — | US | disclosed |
| EP-2318450-A2 | NOVEL CURING AGENTS AND PROCESS FOR THEIR MANUFACTURE | Hexcel Composites Limited (GB) | 2011-05-11 | — | — | EP | disclosed |
| WO-2010018392-A2 | NOVEL CURING AGENTS AND PROCESS FOR THEIR MANUFACTURE | HEXCEL COMPOSITES LIMITED (GB) | 2010-02-18 | — | — | WO | disclosed |
| US-6949589-B2 | Elastic foamed grinder material and method for producing the same | OYAIZU YOSHIJIRO | 2005-09-27 | — | — | US | disclosed |
| US-20030066245-A1 | Elastic foamed grinder material and method for producing the same | OYAIZU YOSHIJIRO (JP) | 2003-04-10 | — | — | US | disclosed |
| US-5955199-A | LAMINATED VEHICLE PART COMPRISING SHEET MOLDING COMPOUND SUBSTRATES ADHERED TOGETHER WITH ADHESIVE COMPRISING ISOCYANATE TERMINATED PREPOLYMER, CURATIVE MIXTURE OF POLYOL, POLYAMINE, POLYKETIMINE OR POLYALDIMINE | ASHLAND INC. (US) | 1999-09-21 | — | — | US | disclosed |
| WO-1999016619-A1 | IMINE-CONTAINING CURATIVE FOR TWO COMPONENT POLYURETHANE STRUCTURAL ADHESIVES | ASHLAND INC. (US) | 1999-04-08 | — | — | WO | disclosed |
| US-5880180-A | THERMOSETTING RESIN COMPOSITION FOR SHEET MOLDING COMPRISING UNSATURATED POLYESTER, UNSATURATED MONOMER, LOW PROFILE ADDITIVE, AROMATIC ALDIMINE SURFACE QUALITY ENHANCER | ASHLAND INC. (US) | 1999-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110130525-A1 | NOVEL CURING AGENTS AND PROCESS FOR THEIR MANUFACTURE | ARCN1, PUF60, RCOR1 | DHFR 1146/4885TAAR1 2691/4885MAP4K1 3882/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.