Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 11/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 7/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 7/20 | 0.43 |
| ▸ | F2 | P00734 | 6/20 | 0.39 |
| ▸ | PLG | P00747 | 5/20 | 0.39 |
| ▸ | PLAU | P00749 | 2/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | KLK1 | P06870 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 2/20 | 0.38 |
| ▸ | PLAT | P00750 | 1/20 | 0.38 |
| ▸ | F12 | P00748 | 1/20 | 0.37 |
| ▸ | F7 | P08709 | 1/20 | 0.37 |
| ▸ | F3 | P13726 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | C1S | P09871 | 3/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8162967 | 0.81 | PRSS1 (0.39) | PRSS1PRSS2PRSS3F2PLG | |
| SCHEMBL8173657 | 0.81 | C1S (0.42) | PRSS1PRSS2PRSS3F2PLG | |
| SCHEMBL8170543 | 0.78 | NR1H4 (0.35) | PRSS1F2PLGRECQLKMT2A | |
| SCHEMBL8556617 | 0.76 | F10 (0.37) | PRSS1PRSS2PRSS3F2PLG | |
| SCHEMBL9004856 | 0.75 | ESR2 (0.39) | PKMKMT2A | |
| SCHEMBL5201643 | 0.75 | PLA2G7 (0.43) | BLMKMT2A | |
| SCHEMBL3912578 | 0.74 | NPC1 (0.35) | PKMKMT2A | |
| SCHEMBL8170510 | 0.74 | NQO2 (0.44) | PRSS1PRSS2PRSS3F2PLG | |
| SCHEMBL8169397 | 0.74 | PRSS1 (0.44) | PRSS1PRSS2PRSS3F2PLG | |
| SCHEMBL1950632 | 0.72 | PRSS1 (0.50) | PRSS1PRSS2PRSS3F2PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114328-A | ANTICOAGULANTS; BLOOD DISORDERS | DUPONT PHARMACEUTICALS COMPANY (US) | 2000-09-05 | — | — | US | disclosed |
| US-5849736-A | Isoxazoline and isoxazole fibrinogen receptor antagonists | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-12-15 | — | — | US | disclosed |
| EP-0730590-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-09-11 | — | — | EP | disclosed |