Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 8/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 5/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 5/20 | 0.37 |
| ▸ | F2 | P00734 | 3/20 | 0.37 |
| ▸ | PLG | P00747 | 3/20 | 0.37 |
| ▸ | C1S | P09871 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.35 |
| ▸ | F7 | P08709 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 2/20 | 0.33 |
| ▸ | KLK1 | P06870 | 2/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
| ▸ | PLAT | P00750 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8162967 | 0.88 | PRSS1 (0.39) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL8170487 | 0.76 | PRSS1 (0.43) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL8173657 | 0.76 | C1S (0.42) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL9030801 | 0.75 | PRSS1 (0.44) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL8169108 | 0.72 | LMNA (0.48) | F10PRSS1PRSS2PRSS3C1S | |
| SCHEMBL1950671 | 0.70 | LMNA (0.43) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL8162971 | 0.69 | C1S (0.57) | PRSS1PRSS2PRSS3F2PLG | |
| SCHEMBL8169397 | 0.69 | PRSS1 (0.44) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL4007973 | 0.69 | NOTUM (0.38) | IDO1 | |
| SCHEMBL7799755 | 0.67 | P2RX7 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832076-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-04-01 | — | — | EP | disclosed |