Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL884696 | 0.90 | POLB (0.34) | ALDH1A1POLBPKMHTR7CNR2 | |
| SCHEMBL885714 | 0.85 | POLB (0.35) | ALDH1A1POLBPKMHTR2ATMEM97 | |
| SCHEMBL884541 | 0.80 | CYP2C19 (0.36) | ALDH1A1PKM | |
| SCHEMBL886810 | 0.80 | CTSK (0.33) | CNR2 | |
| SCHEMBL8174751 | 0.78 | ACP1 (0.37) | ALDH1A1PKMHTR7 | |
| SCHEMBL884768 | 0.77 | SLC6A2 (0.38) | ALDH1A1SIGMAR1 | |
| SCHEMBL885599 | 0.76 | HDAC1 (0.33) | ALDH1A1 | |
| SCHEMBL8169739 | 0.76 | SIGMAR1 (0.36) | CNR2HTR2ATMEM97SIGMAR1 | |
| SCHEMBL884320 | 0.75 | LMNA (0.39) | ALDH1A1PKM | |
| SCHEMBL885631 | 0.75 | CTSK (0.33) | HTR7HTR2ATMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008089005-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-07-24 | — | — | WO | disclosed |