Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TLR4 | O00206 | 3/20 | 0.34 |
| ▸ | CD14 | P08571 | 3/20 | 0.34 |
| ▸ | LY96 | Q9Y6Y9 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8201459 | 0.86 | HTR1A (0.43) | HTR1ACYP3A4SMN1; SMN2TLR4CD14 | |
| SCHEMBL15235861 | 0.86 | CYP3A4 (0.38) | CYP3A4SMN1; SMN2TLR4CD14LY96 | |
| SCHEMBL15235863 | 0.80 | CYP3A4 (0.35) | HTR1ACYP3A4SMN1; SMN2TLR4CD14 | |
| SCHEMBL347042 | 0.75 | HTR1A (0.43) | HTR1ACYP3A4SMN1; SMN2ALDH1A1 | |
| SCHEMBL13130673 | 0.74 | RXRA (0.40) | CYP3A4SMN1; SMN2TLR4CD14LY96 | |
| SCHEMBL7907550 | 0.73 | HTR1A (0.39) | HTR1ACYP3A4SMN1; SMN2ALDH1A1 | |
| SCHEMBL17119054 | 0.72 | CYP1A2 (0.44) | CYP3A4ALDH1A1 | |
| SCHEMBL7908932 | 0.71 | HTR1A (0.40) | HTR1ACYP3A4SMN1; SMN2ALDH1A1 | |
| SCHEMBL17565190 | 0.71 | HTR1A (0.34) | HTR1ACYP3A4ALDH1A1 | |
| SCHEMBL7912707 | 0.71 | HTR1A (0.38) | HTR1ACYP3A4SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9428432-B2 | Derivatives of tris(2-hydroxyphenyl)methanes, preparation thereof and use thereof for mineral oil production | BASF Wintershall Holding GmbH (DE) | 2016-08-30 | — | — | US | disclosed |
| EP-2782666-B1 | DERIVATIVES OF TRIS(2-HYDROXYPHENYL)METHANES, THE PRODUCTION THEREOF AND USE THEREOF FOR OIL PRODUCTION | Wintershall Holding GmbH (DE) | 2016-02-03 | — | — | EP | disclosed |
| US-9212545-B2 | Use of tris(2-hydroxyphenyl)methane derivatives for tertiary mineral oil production | Wintershall Holding GmbH (DE) | 2015-12-15 | — | — | US | disclosed |
| EP-2571923-B1 | DERIVATIVES OF TRIS(2-HYDROXYPHENYL)METHANE, AND PREPARATION AND USE THEREOF | BASF SE (DE) | 2014-12-17 | — | — | EP | disclosed |
| EP-2782666-A1 | DERIVATIVES OF TRIS(2-HYDROXYPHENYL)METHANES, THE PRODUCTION THEREOF AND USE THEREOF FOR OIL PRODUCTION | Wintershall Holding GmbH (DE) | 2014-10-01 | — | — | EP | disclosed |
| EP-2768924-A1 | USE OF TRIS(2-HYDROXYPHENYL)METHANE DERIVATIVES FOR TERTIARY PETROLEUM PRODUCTION | Wintershall Holding GmbH (DE) | 2014-08-27 | — | — | EP | disclosed |
| US-8618321-B2 | Derivatives of tris(2-hydroxyphenyl)methane, their preparation and use | BASF SE (DE) | 2013-12-31 | — | — | US | disclosed |
| US-20130228332-A1 | DERIVATIVES OF TRIS(2-HYDROXYPHENYL)METHANES, PREPARATION THEREOF AND USE THEREOF FOR MINERAL OIL PRODUCTION | BASF Wintershall Holding GmbH | 2013-09-05 | — | — | US | disclosed |
| WO-2013076006-A1 | DERIVATIVES OF TRIS(2-HYDROXYPHENYL)METHANES, THE PRODUCTION THEREOF AND USE THEREOF FOR OIL PRODUCTION | Wintershall Holding GmbH (DE) | 2013-05-30 | — | — | WO | disclosed |
| US-20130098609-A1 | USE OF TRIS(2-HYDROXYPHENYL)METHANE DERIVATIVES FOR TERTIARY MINERAL OIL PRODUCTION | Wintershall Holding GmbH (DE) | 2013-04-25 | — | — | US | disclosed |
| WO-2013057044-A1 | USE OF TRIS(2-HYDROXYPHENYL)METHANE DERIVATIVES FOR TERTIARY PETROLEUM PRODUCTION | Wintershall Holding GmbH (DE) | 2013-04-25 | — | — | WO | disclosed |
| US-20110288322-A1 | DERIVATIVES OF TRIS(2-HYDROXYPHENYL)METHANE, THEIR PREPARATION AND USE | BASF SE (DE) | 2011-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110288322-A1 | DERIVATIVES OF TRIS(2-HYDROXYPHENYL)METHANE, THEIR PREPARATION AND USE | MGMT, HPGDS, TOP2A | HTR1A 967/4885CYP3A4 256/4885SMN1; SMN2 3964/4885 |
| US-20130228332-A1 | DERIVATIVES OF TRIS(2-HYDROXYPHENYL)METHANES, PREPARATION THEREOF AND USE THEREOF FOR MINERAL OIL PRODUCTION | HPGDS, SQLE, HSD17B4 | HTR1A 3081/4885CYP3A4 234/4885SMN1; SMN2 4817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.