Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | PRCP | P42785 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8178811 | 0.88 | ALDH1A1 (0.35) | THRBTSHRALDH1A1 | |
| SCHEMBL8182773 | 0.84 | TSHR (0.34) | THRBTSHRALDH1A1 | |
| SCHEMBL347875 | 0.81 | ALDH1A1 (0.52) | THRBTSHRALDH1A1 | |
| SCHEMBL148783 | 0.81 | ALDH1A1 (0.52) | THRBTSHRALDH1A1SMN1; SMN2MEN1 | |
| Acrylic Acid Ethyl Ester SCHEMBL30960549 | 0.79 | THRB (0.42) | THRBTSHRALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL27000 | 0.78 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL28273630 | 0.78 | THRB (0.55) | THRBTSHRALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL14874 | 0.78 | THRB (0.55) | THRBTSHRALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL8172309 | 0.78 | ALDH1A1 (0.33) | THRBTSHRALDH1A1 | |
| SCHEMBL22684899 | 0.77 | THRB (0.53) | THRBTSHRALDH1A1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6051354-A | MIXING IN A HIGH SHEAR DEVICE A CARRIER CORE AND A CARRIER COATING, AND WHEREIN SAID HIGH SHEAR DEVICE CONTAINS IMPELLERS. | XEROX CORPORATION (US) | 2000-04-18 | — | — | US | disclosed |
| US-5945244-A | Coated carrier | XEROX CORPORATION (US) | 1999-08-31 | — | — | US | disclosed |