SCHEMBL148783

SCHEMBL148783

C=C(C)C(=O)OC.C=C(C)C(=O)OCCN(CC)CC

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.52
THRB P10828 1/20 0.49
TSHR P16473 5/20 0.47
CYP2D6 P10635 3/20 0.40
LMNA P02545 3/20 0.40
CYP1A2 P05177 2/20 0.40
MAOA P21397 1/20 0.40
HTR3A P46098 1/20 0.40
HRH3 Q9Y5N1 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.39
CYP3A4 P08684 2/20 0.39
BLM P54132 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
CHRM2 P08172 4/20 0.38
CHRM1 P11229 3/20 0.38
CHRM3 P20309 3/20 0.38
SCN1A P35498 2/20 0.38
SCN2A Q99250 2/20 0.38
SCN3A Q9NY46 2/20 0.38
CHRM4 P08173 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28273630 0.93 THRB (0.55) ALDH1A1THRBTSHRCYP2D6LMNA
SCHEMBL14874 0.93 THRB (0.55) ALDH1A1THRBTSHRCYP2D6LMNA
SCHEMBL22684899 0.91 THRB (0.53) ALDH1A1THRBTSHRCYP2D6LMNA
Hydrochloric Acid SCHEMBL2847352 0.91 THRB (0.53) ALDH1A1THRBTSHRCYP2D6LMNA
SCHEMBL9800939 0.91 THRB (0.53) ALDH1A1THRBTSHRCYP2D6LMNA
Acetic Acid SCHEMBL10336380 0.89 THRB (0.52) ALDH1A1THRBTSHRCYP2D6LMNA
Chloromethane SCHEMBL1128072 0.89 THRB (0.52) ALDH1A1THRBTSHRCYP2D6LMNA
SCHEMBL10697522 0.89 THRB (0.55) ALDH1A1THRBTSHRCYP2D6LMNA
SCHEMBL4635102 0.89 TSHR (0.65) ALDH1A1THRBTSHRCYP2D6CYP1A2
Boric Acid SCHEMBL8763859 0.88 THRB (0.50) ALDH1A1THRBTSHRCYP2D6LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4333815-A1 TASTE MASKED COMPOSTIONS OF 2,4,6-TRIFLUORO- N-[6-(1-METHYL-PIPERIDINE-4-CARBONYL)-PYRIDIN-2- YLJ-BENZAMIDE HEMISUCCINATE, AND ORALLY DISENTEGRATING TABLET COMPRISING THE SAME ELI LILLY AND COMPANY (US) 2024-03-13 EP claimed
WO-2022236004-A1 TASTE MASKED COMPOSTIONS OF 2,4,6-TRIFLUORO- N-[6-(1-METHYL-PIPERIDINE-4-CARBONYL)-PYRIDIN-2- YLJ-BENZAMIDE HEMISUCCINATE, AND ORALLY DISENTEGRATING TABLET COMPRISING THE SAME ELI LILLY AND COMPANY (US) 2022-11-10 WO claimed
EP-4482081-A1 ENVIRONMENTAL ATTRIBUTES FOR PHARMACEUTICAL EXCIPIENTS BASF SE (DE) 2024-12-25 EP disclosed
US-12023226-B2 Methods and devices for skin tightening CYTRELLIS BIOSYSTEMS, INC. (US) 2024-07-02 US disclosed
US-20240197661-A1 ORAL DOSAGE FORMS OF METHYL HYDROGEN FUMARATE AND PRODRUGS THEREOF HPS INVESTMENT PARTNERS, LLC, AS ADMINISTRATIVE AGENT 2024-06-20 US disclosed
US-20240165035-A1 COATED SOLID PHARMACEUTICAL PREPARATION SSP CO., LTD. (JP) 2024-05-23 US disclosed
WO-2024027794-A1 TASTE-MASKING MICROSPHERE, PREPARATION PROCESS THEREFOR, AND USE THEREOF 哈尔滨市康隆药业有限责任公司 2024-02-08 WO disclosed
US-20240024249-A1 ORAL DOSAGE FORMS HAVING A HIGH LOADING OF A METHYL HYDROGEN FUMARATE PRODRUG HPS INVESTMENT PARTNERS, LLC, AS ADMINISTRATIVE AGENT 2024-01-25 US disclosed
EP-4308094-A1 COATED SOLID PHARMACEUTICAL PREPARATION SSP Co., Ltd. (JP) 2024-01-24 EP disclosed
US-20230310222-A1 METHODS AND DEVICES FOR SKIN TIGHTENING D1 CAPITAL PARTNERS, L.P. 2023-10-05 US disclosed
WO-2023176783-A1 SOLID COMPOSITION 第一三共ヘルスケア株式会社 2023-09-21 WO disclosed
US-20120059054-A1 Use Of Copolymers Based On Amino-Containing Polymers As Matrix Binders In Preparing Active Compound-Containing Granules And Administration Forms BASF SE (DE) 2012-03-08 US disclosed
WO-2011051155-A2 STABLE PROTECTIVE COATINGS FOR PHARMACEUTICAL DOSAGE FORMS BASF SE (DE) 2011-05-05 WO disclosed
US-6423460-B1 INORGANIC POLYMER AND ORGANOMETALLIC POLYMER BLEND OF XEROX CORPORATION 2002-07-23 US disclosed
US-6051354-A MIXING IN A HIGH SHEAR DEVICE A CARRIER CORE AND A CARRIER COATING, AND WHEREIN SAID HIGH SHEAR DEVICE CONTAINS IMPELLERS. XEROX CORPORATION (US) 2000-04-18 US disclosed
US-6037091-A Carrier with ferrocene containing polymer XEROX CORPORATION (US) 2000-03-14 US disclosed
EP-0232442-B1 IMPROVED BLOOD-PURIFYING MEMBRANE AND PROCESS FOR PREPARATION THEREOF Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1989-04-26 EP disclosed
US-4787977-A REGENERATED CELLULOSE WITH AMINO CONTAINING POLYMERIC COATING ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1988-11-29 US disclosed
EP-0232442-A1 Improved blood-purifying membrane and process for preparation thereof Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1987-08-19 EP disclosed
US-4255308-A A DISPERSION COMPRISING A BINDER OF A METHYL METHACRYLATE POLYMER, A DISPERSANT OF AN ACRYLIC TERPOLYMER, AND A GRAFT POLYMER OF THE TWO; FINISHES FOR CARS AND TRUCKS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-03-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240024249-A1 ORAL DOSAGE FORMS HAVING A HIGH LOADING OF A METHYL HYDROGEN FUMARATE PRODRUG FH, MGMT, CYP4F2 ALDH1A1 1240/4885THRB 4233/4885TSHR 4391/4885
US-20240197661-A1 ORAL DOSAGE FORMS OF METHYL HYDROGEN FUMARATE AND PRODRUGS THEREOF MGMT, MTHFD2, PHF2 ALDH1A1 2175/4885THRB 4158/4885TSHR 4207/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.