Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9530470 | 0.86 | MAPT (0.50) | TDP1MEN1MAPTKMT2APPARG | |
| SCHEMBL7986932 | 0.82 | MAPT (0.61) | TDP1MEN1MAPTKMT2APPARG | |
| SCHEMBL9630761 | 0.81 | TDP1 (0.48) | TDP1MEN1MAPTKMT2APPARG | |
| SCHEMBL9530722 | 0.81 | TDP1 (0.36) | TDP1MEN1MAPTKMT2APPARG | |
| SCHEMBL20822166 | 0.79 | AKT1 (0.36) | TDP1MEN1MAPTKMT2ATSHR | |
| SCHEMBL7487350 | 0.78 | MEN1 (0.52) | TDP1MEN1MAPTKMT2APPARG | |
| SCHEMBL7842499 | 0.76 | MEN1 (0.56) | TDP1MEN1MAPTKMT2APPARG | |
| SCHEMBL15150899 | 0.75 | NPC1 (0.43) | TDP1MEN1MAPTKMT2APPARG | |
| SCHEMBL16282030 | 0.75 | MEN1 (0.40) | TDP1MEN1MAPTKMT2APPARG | |
| SCHEMBL16282031 | 0.75 | ALOX5 (0.37) | TDP1MEN1MAPTKMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000008009-A1 | PROCESS FOR THE PREPARATION OF 2-(AMINOPHENOXYMETHYL) CHROMANS | SANKYO COMPANY, LIMITED (JP) | 2000-02-17 | — | — | WO | disclosed |