Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 5/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5014183 | 0.90 | SLC6A2 (0.46) | CACNA1GCTSSCTSKTSHRLMNA | |
| SCHEMBL8174332 | 0.82 | ALDH1A1 (0.46) | CTSSCTSKTSHRLMNAMEN1 | |
| SCHEMBL8174330 | 0.82 | ALDH1A1 (0.46) | CTSSCTSKTSHRLMNAMEN1 | |
| SCHEMBL5014055 | 0.81 | CTSK (0.43) | CTSSCTSKTSHRLMNAMEN1 | |
| SCHEMBL8184215 | 0.81 | TSHR (0.41) | CTSSCTSKTSHRLMNAMEN1 | |
| SCHEMBL1196722 | 0.79 | ACE (0.45) | CTSSCTSKSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7615051 | 0.76 | TSHR (0.43) | CTSSCTSKTSHRLMNAMEN1 | |
| SCHEMBL5013656 | 0.74 | PCSK9 (0.46) | CACNA1GKCNH2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL12980639 | 0.74 | C3AR1 (0.46) | CTSKTSHRLMNAMEN1KMT2A | |
| SCHEMBL10045822 | 0.74 | C3AR1 (0.46) | CTSKTSHRLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6156732-A | Azole peptidomimetics as thrombin receptor antagonists | ORTHO-MCNEIL PHARMACEUTICALS, INC. (US) | 2000-12-05 | — | — | US | disclosed |
| US-6017890-A | Azole peptidomimetics as thrombin receptor antagonists | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2000-01-25 | — | — | US | disclosed |