Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CTSS | P25774 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5014183 | 0.91 | SLC6A2 (0.46) | CTSKALDH1A1CTSSNPSR1TSHR | |
| SCHEMBL9303530 | 0.82 | ATM (0.39) | CTSKALDH1A1CTSSNPSR1TSHR | |
| SCHEMBL8174337 | 0.81 | CACNA1G (0.46) | CTSKALDH1A1CTSSNPSR1TSHR | |
| SCHEMBL5014051 | 0.80 | ALDH1A1 (0.58) | CTSKALDH1A1CTSSNPSR1TSHR | |
| SCHEMBL16763395 | 0.77 | CHRM3 (0.64) | — | |
| SCHEMBL16763393 | 0.77 | CHRM3 (0.64) | — | |
| SCHEMBL5013649 | 0.77 | PCSK9 (0.47) | CTSKCTSSNPSR1HTTMEN1 | |
| SCHEMBL31633750 | 0.76 | ALDH1A1 (0.48) | CTSKALDH1A1CTSSNPSR1TSHR | |
| SCHEMBL7723269 | 0.76 | MAPT (0.48) | CTSKALDH1A1CTSSNPSR1TSHR | |
| SCHEMBL16602128 | 0.75 | C3AR1 (0.49) | ALDH1A1NPSR1TSHRLMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008009942-A1 | HETEROAROMATIC-BASED PEPTIDE MACROCYCLES AS G-QUADRUPLEX LIGANDS | CAMBRIDGE ENTERPRISE LTD. (GB) | 2008-01-24 | — | — | WO | disclosed |