Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 1/20 | 0.49 |
| ▸ | NQO2 | P16083 | 6/20 | 0.45 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | F12 | P00748 | 1/20 | 0.41 |
| ▸ | F7 | P08709 | 1/20 | 0.41 |
| ▸ | F3 | P13726 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | C1S | P09871 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TOP1 | P11387 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2956882 | 0.77 | GPR3 (0.37) | ALDH1A1 | |
| SCHEMBL27552294 | 0.76 | F10 (0.40) | WDR5NQO2F2F10F12 | |
| SCHEMBL21295742 | 0.71 | NOTUM (0.40) | KMT2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL2967968 | 0.69 | GSTP1 (0.39) | ALDH1A1HPGD | |
| SCHEMBL4021876 | 0.67 | WDR5 (1.00) | WDR5NQO2F2F10F12 | |
| SCHEMBL394218 | 0.66 | WDR5 (0.80) | WDR5NQO2F2F10F12 | |
| SCHEMBL8973288 | 0.66 | WDR5 (0.80) | WDR5NQO2F2F10F12 | |
| SCHEMBL5877790 | 0.66 | GPR3 (0.33) | ALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL6029673 | 0.66 | WDR5 (0.95) | WDR5NQO2F2F10F12 | |
| SCHEMBL6956581 | 0.65 | HDAC8 (0.58) | WDR5NQO2F2F10F12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114328-A | ANTICOAGULANTS; BLOOD DISORDERS | DUPONT PHARMACEUTICALS COMPANY (US) | 2000-09-05 | — | — | US | disclosed |