SCHEMBL8973288

SCHEMBL8973288

N=C(N)c1ccc(-c2ccc(C(=N)N)cc2)cc1

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
WDR5 P61964 1/20 0.80
ALDH1A1 P00352 2/20 0.65
HPGD P15428 2/20 0.65
HSD17B10 Q99714 2/20 0.65
PRMT1 Q99873 2/20 0.65
NQO2 P16083 2/20 0.65
TOP1 P11387 1/20 0.65
CASP1 P29466 1/20 0.65
CASP7 P55210 1/20 0.65
TDP1 Q9NUW8 1/20 0.65
LMNA P02545 2/20 0.65
PLAU P00749 2/20 0.65
MASP2 O00187 1/20 0.65
THPO P40225 1/20 0.65
TOP2A P11388 1/20 0.62
TOP2B Q02880 1/20 0.62
F2 P00734 3/20 0.62
PRSS1 P07477 2/20 0.62
PRSS3 P35030 2/20 0.62
APEX1 P27695 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL394218 1.00 WDR5 (0.80) WDR5ALDH1A1HPGDHSD17B10PRMT1
SCHEMBL537030 0.90 LMNA (0.77) WDR5ALDH1A1HPGDHSD17B10PRMT1
SCHEMBL4021876 0.89 WDR5 (1.00) WDR5ALDH1A1HPGDHSD17B10PRMT1
Hydrochloric Acid SCHEMBL6029673 0.87 WDR5 (0.95) WDR5ALDH1A1HPGDHSD17B10PRMT1
SCHEMBL1714557 0.87 WDR5 (0.64) WDR5ALDH1A1HPGDHSD17B10PRMT1
SCHEMBL12461484 0.87 WDR5 (0.64) WDR5ALDH1A1HPGDHSD17B10PRMT1
SCHEMBL27438192 0.87 WDR5 (0.64) WDR5ALDH1A1HPGDHSD17B10PRMT1
Hydrochloric Acid SCHEMBL30999366 0.87 PRSS1 (0.78) WDR5ALDH1A1HPGDHSD17B10PRMT1
Hydrochloric Acid SCHEMBL392375 0.87 PRSS1 (0.78) WDR5ALDH1A1HPGDHSD17B10PRMT1
SCHEMBL25090641 0.85 WDR5 (0.61) WDR5ALDH1A1HPGDHSD17B10PRMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119352066-A Covalent triazine frame/weak acid gallium salt compound and electrocatalytic hydrogen peroxide production catalyst 三峡大学 2025-01-24 CN claimed
CN-119352096-A Preparation method of magnesium-modified porous material catalyst and catalyst for catalyzing hydrogen peroxide production 三峡大学 2025-01-24 CN claimed
CN-118932406-A Covalent triazine frame/basic bismuth salt compound and application thereof in electrocatalytic hydrogen peroxide production 三峡大学 2024-11-12 CN claimed
CN-118341407-A Preparation method and adsorption application of tetrathiafulvalene-based metal organic framework material 重庆文理学院 2024-07-16 CN claimed
CN-117866219-A Construction of TM-N 4 Method for promoting oxygen reduction reaction by atomic site 三峡大学 2024-04-12 CN claimed
CN-115094463-B Sub-nano alloy material and preparation method and application thereof 中国科学院上海高等研究院 2023-10-13 CN claimed
CN-115094463-A Sub-nanometer alloy material and preparation method and application thereof 中国科学院上海高等研究院 2022-09-23 CN claimed
CN-110628038-A Covalent triazine organic framework, limited-area metal catalyst, preparation method and application 中国科学院上海高等研究院 2019-12-31 CN claimed
CN-119352096-A Preparation method of magnesium-modified porous material catalyst and catalyst for catalyzing hydrogen peroxide production 三峡大学 2025-01-24 CN disclosed
CN-119352066-A Covalent triazine frame/weak acid gallium salt compound and electrocatalytic hydrogen peroxide production catalyst 三峡大学 2025-01-24 CN disclosed
CN-118932406-A Covalent triazine frame/basic bismuth salt compound and application thereof in electrocatalytic hydrogen peroxide production 三峡大学 2024-11-12 CN disclosed
CN-117866219-A Construction of TM-N 4 Method for promoting oxygen reduction reaction by atomic site 三峡大学 2024-04-12 CN disclosed
CN-115094463-B Sub-nano alloy material and preparation method and application thereof 中国科学院上海高等研究院 2023-10-13 CN disclosed
CN-115094463-A Sub-nanometer alloy material and preparation method and application thereof 中国科学院上海高等研究院 2022-09-23 CN disclosed
US-7964619-B2 Teraryl components as antiparasitic agents THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2011-06-21 US disclosed
US-7964619-B2 Teraryl components as antiparasitic agents THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2011-06-21 US disclosed
WO-2010078867-A1 METHOD FOR IMPROVED BIOACTIVATION OF MEDICATIONS CHRISTIAN-ALBRECHTS-UNIVERSITÄT ZU KIEL (DE) 2010-07-15 WO disclosed
EP-1949896-A2 Linear dicationic terphenyls and their aza analogues as antiparasitic agents The University of North Carolina At Chapel Hill (US) 2008-07-30 EP disclosed
US-20070232621-A1 Linear dicationic terphenyls and their aza analogues as antiparasitic agents GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2007-10-04 US disclosed
US-20070232621-A1 Linear dicationic terphenyls and their aza analogues as antiparasitic agents GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2007-10-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070232621-A1 Linear dicationic terphenyls and their aza analogues as antiparasitic agents TPMT, TYMS, DDT WDR5 1295/4885ALDH1A1 2647/4885HPGD 4029/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.