SCHEMBL394218

SCHEMBL394218

N=C(N)c1ccc(-c2ccc(-c3ccc(C(=N)N)cc3)cc2)cc1

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ WDR5 P61964 1/20 0.80
▸ ALDH1A1 P00352 2/20 0.65
▸ HPGD P15428 2/20 0.65
▸ HSD17B10 Q99714 2/20 0.65
▸ PRMT1 Q99873 2/20 0.65
▸ NQO2 P16083 2/20 0.65
▸ TOP1 P11387 1/20 0.65
▸ CASP1 P29466 1/20 0.65
▸ CASP7 P55210 1/20 0.65
▸ TDP1 Q9NUW8 1/20 0.65
▸ LMNA P02545 2/20 0.65
▸ PLAU P00749 2/20 0.65
▸ MASP2 O00187 1/20 0.65
▸ THPO P40225 1/20 0.65
▸ TOP2A P11388 1/20 0.62
▸ TOP2B Q02880 1/20 0.62
▸ F2 P00734 3/20 0.62
▸ PRSS1 P07477 2/20 0.62
▸ PRSS3 P35030 2/20 0.62
▸ APEX1 P27695 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8973288 1.00 WDR5 (0.80) WDR5ALDH1A1HPGDHSD17B10PRMT1
SCHEMBL537030 0.90 LMNA (0.77) WDR5ALDH1A1HPGDHSD17B10PRMT1
SCHEMBL4021876 0.89 WDR5 (1.00) WDR5ALDH1A1HPGDHSD17B10PRMT1
SCHEMBL12461484 0.87 WDR5 (0.64) WDR5ALDH1A1HPGDHSD17B10PRMT1
SCHEMBL1714557 0.87 WDR5 (0.64) WDR5ALDH1A1HPGDHSD17B10PRMT1
SCHEMBL27438192 0.87 WDR5 (0.64) WDR5ALDH1A1HPGDHSD17B10PRMT1
Hydrochloric Acid SCHEMBL6029673 0.87 WDR5 (0.95) WDR5ALDH1A1HPGDHSD17B10PRMT1
Hydrochloric Acid SCHEMBL392375 0.87 PRSS1 (0.78) WDR5ALDH1A1HPGDHSD17B10PRMT1
Hydrochloric Acid SCHEMBL30999366 0.87 PRSS1 (0.78) WDR5ALDH1A1HPGDHSD17B10PRMT1
SCHEMBL25090641 0.85 WDR5 (0.61) WDR5ALDH1A1HPGDHSD17B10PRMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060293328-A1 Linear dicationic terphenyls and their aza analogues as antiparasitic agents TIDWELL RICHARD R 2006-12-28 — — US claimed
EP-1736466-A1 Linear dicationic terphenyls and their aza analogues as antiparasitic agents The University of North Carolina at Chapel Hill (US) 2006-12-27 — — EP claimed
CN-113442919-B Vehicle following system and information processing method 本田技研工业株式会社 2024-07-23 — — CN disclosed
CN-115210124-A Vehicle follow-up running system, information processing device, information processing method, and program 本田技研工业株式会社 2022-10-18 — — CN disclosed
CN-115208991-A Electronic device, setting management system and method, storage medium, and computer apparatus 株式会社理光 2022-10-18 — — CN disclosed
CN-115135553-A Vehicle follow-up running system, information processing method, and program 本田技研工业株式会社 2022-09-30 — — CN disclosed
EP-3042718-A1 DEVICE FOR SOLUBILIZING, SEPARATING, REMOVING AND REACTING CARBOXYLIC ACIDS IN OILS, FATS, AQUEOUS OR ORGANIC SOLUTIONS BY MEANS OF MICRO- OR NANOEMULSIFICATION Dietz, Ulrich (DE) 2016-07-13 — — EP disclosed
US-20160122686-A1 DEVICE AND METHOD FOR SOLUBILIZING, SEPARATING, REMOVING AND REACTING CARBOXYLIC ACIDS IN OILS, FATS, AQUEOUS OR ORGANIC SOLUTIONS BY MEANS OF MICRO-OR NANOEMULSIFICATION DIETZ ULRICH (DE) 2016-05-05 — — US disclosed
EP-2585420-B1 METHOD FOR SOLUBILIZING, SEPARATING, REMOVING AND REACTING CARBOXYLIC ACIDS IN OILS, FATS, AQUEOUS OR ORGANIC SOLUTIONS BY MEANS OF MICRO- OR NANOEMULSIFICATION DIETZ ULRICH (DE) 2016-04-06 — — EP disclosed
US-9127233-B2 Device and method for solubilizing, separating, removing and reacting carboxylic acids in oils, fats, aqueous or organic solutions by means of micro-or nanoemulsification Dietz, Ulrich (DE) 2015-09-08 — — US disclosed
EP-2585420-A2 DEVICE AND METHOD FOR SOLUBILIZING, SEPARATING, REMOVING AND REACTING CARBOXYLIC ACIDS IN OILS, FATS, AQUEOUS OR ORGANIC SOLUTIONS BY MEANS OF MICRO- OR NANOEMULSIFICATION Dietz, Ulrich (DE) 2013-05-01 — — EP disclosed
US-7964619-B2 Teraryl components as antiparasitic agents THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2011-06-21 — — US disclosed
US-7964619-B2 Teraryl components as antiparasitic agents THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2011-06-21 — — US disclosed
US-7964619-B2 Teraryl components as antiparasitic agents THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2011-06-21 — — US disclosed
EP-1949896-A2 Linear dicationic terphenyls and their aza analogues as antiparasitic agents The University of North Carolina At Chapel Hill (US) 2008-07-30 — — EP disclosed
US-20070232621-A1 Linear dicationic terphenyls and their aza analogues as antiparasitic agents GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2007-10-04 — — US disclosed
US-20070232621-A1 Linear dicationic terphenyls and their aza analogues as antiparasitic agents GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2007-10-04 — — US disclosed
US-20070232621-A1 Linear dicationic terphenyls and their aza analogues as antiparasitic agents GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2007-10-04 — — US disclosed
US-20060293328-A1 Linear dicationic terphenyls and their aza analogues as antiparasitic agents TIDWELL RICHARD R 2006-12-28 — — US disclosed
EP-1736466-A1 Linear dicationic terphenyls and their aza analogues as antiparasitic agents The University of North Carolina at Chapel Hill (US) 2006-12-27 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070232621-A1 Linear dicationic terphenyls and their aza analogues as antiparasitic agents TPMT, TYMS, DDT WDR5 1295/4885ALDH1A1 2647/4885HPGD 4029/4885
US-20060293328-A1 Linear dicationic terphenyls and their aza analogues as antiparasitic agents TPMT, TYMS, DDT WDR5 1295/4885ALDH1A1 2647/4885HPGD 4029/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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