Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 12/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27467431 | 0.75 | ALDH1A1 (0.46) | GLSSMN1; SMN2 | |
| SCHEMBL7371609 | 0.74 | GLS (0.40) | GLS | |
| SCHEMBL7369314 | 0.71 | GLS (0.35) | GLS | |
| SCHEMBL7020662 | 0.63 | DAO (0.35) | — | |
| SCHEMBL17967116 | 0.61 | FFAR1 (0.52) | — | |
| SCHEMBL19793299 | 0.61 | FFAR1 (0.47) | GLSSMN1; SMN2 | |
| SCHEMBL8840294 | 0.61 | MEN1 (0.47) | HTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11595879 | 0.61 | GPR35 (0.33) | — | |
| SCHEMBL19793298 | 0.60 | GLS (0.49) | GLSSMN1; SMN2 | |
| SCHEMBL31497061 | 0.58 | NPSR1 (0.51) | GLSSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153628-A | 1,3,4-thiadiazoles and 1,3,4-Oxadiazoles as αv β3 antagonists | DUPONT PHARMACEUTICALS COMPANY (US) | 2000-11-28 | — | — | US | disclosed |