SCHEMBL8175657

SCHEMBL8175657

O=c1ccn(-c2cccc3ccoc23)c(=O)[nH]1

nearest known ligand 0.47

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 2/20 0.44
DDB1 Q16531 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26684295 0.75 CRBN (0.42) CRBNDDB1
SCHEMBL8948735 0.72 HTR1A (0.35)
SCHEMBL25565848 0.70 CRBN (0.56) CRBNDDB1
SCHEMBL2266044 0.69 TLR9 (0.50)
SCHEMBL8175658 0.69 HTR1A (0.36)
Hydrochloric Acid SCHEMBL2263189 0.68 TLR9 (0.48)
SCHEMBL27732654 0.68 CRBN (0.49) CRBNDDB1
SCHEMBL26683611 0.68 CRBN (0.49) CRBNDDB1
SCHEMBL8018395 0.67 CRBN (0.56) CRBNDDB1
SCHEMBL2709043 0.67 CRBN (0.56) CRBNDDB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6130187-A Benzofuran-7-yl uracil derivatives and herbicides KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2000-10-10 US claimed
EP-0881223-A1 BENZOFURAN-7-YLURACIL DERIVATIVES AND HERBICIDES KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1998-12-02 EP claimed
US-6130187-A Benzofuran-7-yl uracil derivatives and herbicides KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2000-10-10 US disclosed
US-6130187-A Benzofuran-7-yl uracil derivatives and herbicides KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2000-10-10 US disclosed
US-6130187-A Benzofuran-7-yl uracil derivatives and herbicides KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2000-10-10 US disclosed
EP-0881223-A4 BENZOFURAN-7-YLURACIL DERIVATIVES AND HERBICIDES KUMIAI CHEMICAL INDUSTRY CO (JP) 1999-04-14 EP disclosed
EP-0881223-A1 BENZOFURAN-7-YLURACIL DERIVATIVES AND HERBICIDES KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1998-12-02 EP disclosed
EP-0881223-A1 BENZOFURAN-7-YLURACIL DERIVATIVES AND HERBICIDES KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1998-12-02 EP disclosed
WO-1997029105-A1 BENZOFURAN-7-YLURACIL DERIVATIVES AND HERBICIDES KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1997-08-14 WO disclosed