SCHEMBL8175658

SCHEMBL8175658

O=c1cc[nH]c(=O)n1-c1cccc2ccoc12

nearest known ligand 0.46

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 1/20 0.36
DRD2 P14416 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6970035 0.77 MAPK14 (0.34)
SCHEMBL7229298 0.75 AHR (0.42)
SCHEMBL6965571 0.74 ELANE (0.34)
SCHEMBL9275529 0.73 BCAT1 (0.48)
SCHEMBL16320025 0.70 JAK2 (0.42)
SCHEMBL6344180 0.69 HTR1A (0.42) HTR1ADRD2
SCHEMBL8110269 0.69 ADRB1 (0.47) DRD2
SCHEMBL8175657 0.69 CRBN (0.44)
SCHEMBL2266044 0.68 TLR9 (0.50)
SCHEMBL11378918 0.68 MAPK8 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6130187-A Benzofuran-7-yl uracil derivatives and herbicides KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2000-10-10 US claimed
EP-0881223-A1 BENZOFURAN-7-YLURACIL DERIVATIVES AND HERBICIDES KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1998-12-02 EP claimed
US-6130187-A Benzofuran-7-yl uracil derivatives and herbicides KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2000-10-10 US disclosed
US-6130187-A Benzofuran-7-yl uracil derivatives and herbicides KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2000-10-10 US disclosed
US-6130187-A Benzofuran-7-yl uracil derivatives and herbicides KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2000-10-10 US disclosed
EP-0881223-A4 BENZOFURAN-7-YLURACIL DERIVATIVES AND HERBICIDES KUMIAI CHEMICAL INDUSTRY CO (JP) 1999-04-14 EP disclosed
EP-0881223-A1 BENZOFURAN-7-YLURACIL DERIVATIVES AND HERBICIDES KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1998-12-02 EP disclosed
EP-0881223-A1 BENZOFURAN-7-YLURACIL DERIVATIVES AND HERBICIDES KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1998-12-02 EP disclosed
WO-1997029105-A1 BENZOFURAN-7-YLURACIL DERIVATIVES AND HERBICIDES KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1997-08-14 WO disclosed