Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 4/20 | 0.35 |
| ▸ | FBP1 | P09467 | 10/20 | 0.35 |
| ▸ | ITGAV | P06756 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8176184 | 1.00 | GLS (0.37) | GLSMEN1CYP3A4MAPTCYP2C9 | |
| SCHEMBL8210927 | 0.89 | F2 (0.40) | GLSMEN1CYP3A4MAPTCYP2C9 | |
| SCHEMBL8210925 | 0.89 | F2 (0.40) | GLSMEN1CYP3A4MAPTCYP2C9 | |
| SCHEMBL8216119 | 0.81 | ITGB3 (0.39) | GLSF2ITGAV | |
| SCHEMBL8216110 | 0.80 | F2 (0.33) | GLSMEN1CYP3A4MAPTCYP2C9 | |
| SCHEMBL8177325 | 0.73 | ITGB3 (0.46) | F2ITGAV | |
| SCHEMBL8177319 | 0.72 | ITGB3 (0.36) | GLSF2FBP1ITGAV | |
| Hydrochloric Acid SCHEMBL8222330 | 0.72 | ITGB3 (0.36) | GLSF2FBP1ITGAV | |
| SCHEMBL8167396 | 0.69 | GLS (0.38) | GLS | |
| SCHEMBL7379009 | 0.67 | KMT2A (0.49) | KMT2AF2FBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153628-A | 1,3,4-thiadiazoles and 1,3,4-Oxadiazoles as αv β3 antagonists | DUPONT PHARMACEUTICALS COMPANY (US) | 2000-11-28 | — | — | US | disclosed |