Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7453712 | 0.65 | TP53 (0.38) | ALDH1A1MAPTMEN1KMT2ACYP2C19 | |
| SCHEMBL7455149 | 0.65 | TP53 (0.38) | ALDH1A1MAPTMEN1KMT2ACYP2C19 | |
| SCHEMBL5889135 | 0.63 | SPPL2A (0.47) | LMNACYP3A4 | |
| SCHEMBL5981554 | 0.63 | MCL1 (0.39) | LMNAMAPTMEN1KMT2AGAA | |
| SCHEMBL17258893 | 0.62 | ALDH1A1 (0.53) | POLBALDH1A1MEN1KMT2AGAA | |
| SCHEMBL2755880 | 0.61 | FABP3 (0.67) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL21048978 | 0.60 | TP53 (0.52) | ALDH1A1MEN1KMT2AGAATP53 | |
| SCHEMBL21048854 | 0.60 | PTGER1 (0.44) | ALDH1A1KMT2AGAATP53 | |
| SCHEMBL21048781 | 0.60 | C5AR1 (0.50) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL7458622 | 0.60 | RORC (0.45) | POLBALDH1A1LMNACYP3A4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6156768-A | Alpha- and beta-amino acid hydroxyethylamino sulfamic acid derivatives useful as retroviral protease inhibitors | G. D. SEARLE & CO. (US) | 2000-12-05 | — | — | US | disclosed |