Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 2/20 | 0.50 |
| ▸ | WNT3A | P56704 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 6/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 3/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29421022 | 0.89 | ACHE (0.53) | LMNAACHEALDH1A1MAPTBCHE | |
| SCHEMBL480430 | 0.89 | ACHE (0.53) | LMNAACHEALDH1A1MAPTBCHE | |
| SCHEMBL1849440 | 0.84 | MAPT (0.47) | LMNAACHEALDH1A1MAPTBCHE | |
| SCHEMBL4652464 | 0.82 | ACHE (0.47) | ACHEALDH1A1BCHECYP3A4POLB | |
| SCHEMBL21706301 | 0.80 | ACHE (0.45) | ACHEALDH1A1BCHECYP3A4TSHR | |
| SCHEMBL9315365 | 0.80 | ACHE (0.51) | LMNAACHEALDH1A1MAPTBCHE | |
| SCHEMBL7943207 | 0.80 | LMNA (0.47) | LMNAACHEALDH1A1MAPTBCHE | |
| SCHEMBL8176376 | 0.79 | HPGD (0.47) | ACHEBCHETSHRPOLB | |
| SCHEMBL8776056 | 0.79 | ACHE (0.42) | LMNAACHEALDH1A1MAPTBCHE | |
| SCHEMBL3681592 | 0.79 | PTPN1 (0.39) | ALDH1A1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5306600-A | Oxygen-containing titanocenes, and the use thereof | CIBA-GEIGY CORPORATION (US) | 1994-04-26 | — | — | US | disclosed |
| US-5192642-A | Photoinitiators for addition photopolymerization, coatings | CIBA-GEIGY CORPORATION (US) | 1993-03-09 | — | — | US | disclosed |
| US-5068371-A | Photoinitiators for polymerization | CIBA-GEIGY CORPORATION (US) | 1991-11-26 | — | — | US | disclosed |