Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ACMSD | Q8TDX5 | 3/20 | 0.38 |
| ▸ | HNF4A | P41235 | 2/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | KMO | O15229 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8570528 | 0.87 | KDM4E (0.30) | ALDH1A1 | |
| SCHEMBL6640010 | 0.81 | CA2 (0.47) | ACMSDHNF4ADHFRMCL1HDAC8 | |
| SCHEMBL5237975 | 0.81 | PTGS2 (0.39) | PTPN1SMN1; SMN2ACMSDHNF4ADHFR | |
| SCHEMBL7403541 | 0.77 | PTPN1 (0.41) | PTPN1SMN1; SMN2ACMSDHNF4ADHFR | |
| SCHEMBL6643221 | 0.77 | HTR6 (0.39) | TSHRL3MBTL1PFKFB3ACLY | |
| SCHEMBL28428524 | 0.77 | ALDH1A1 (0.42) | MCL1MEN1NPC1LMNAMAPT | |
| SCHEMBL2152786 | 0.75 | ALDH1A1 (0.44) | TSHRMEN1LMNAMAPTTHRB | |
| SCHEMBL11141080 | 0.74 | PTPN1 (0.37) | PTPN1SMN1; SMN2TSHRACMSDHNF4A | |
| SCHEMBL7465376 | 0.74 | MAPT (0.41) | SMN1; SMN2MEN1NPC1LMNAMAPT | |
| SCHEMBL7392188 | 0.73 | KDM4E (0.33) | SMN1; SMN2MEN1NPC1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6090163-A | SYNERGISTIC MIXTURE OF AZO DYES OF GIVEN FORMULAS IN GIVEN MOLAR RATIO; HIGH COLOR STRENGTH; EACH DYE HAS A FIBER-REACTIVE RADICAL OF THE VINYL SULFONE SERIES ATTACHED TO THE BENZENE NUCLEUS META OR PARA THE AZO GROUP | DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) | 2000-07-18 | — | — | US | disclosed |
| US-4560709-A | CONTAINING DUAL CATALYST OF AROMATIC IODONIUM SALT AND AROMATIC OXY KETONE | CIBA GEIGY CORPORATION (US) | 1985-12-24 | — | — | US | disclosed |