Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8182360 | 0.95 | CNR2 (0.43) | CNR2FAAHPOLBHTTALDH1A1 | |
| SCHEMBL8185414 | 0.92 | KMT2A (0.49) | POLBALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL8186092 | 0.92 | FAAH (0.43) | CNR2FAAHPOLBHTTALDH1A1 | |
| SCHEMBL5122824 | 0.87 | PRKCI (0.46) | CNR2PDE5A | |
| SCHEMBL8177717 | 0.87 | PRKCI (0.44) | CNR2FAAHPOLBHTTALDH1A1 | |
| SCHEMBL8183436 | 0.86 | LMNA (0.43) | CNR2FAAHPOLBHTTALDH1A1 | |
| SCHEMBL8184338 | 0.85 | CNR2 (0.42) | CNR2FAAHPOLBHTTALDH1A1 | |
| SCHEMBL8176873 | 0.85 | PRKCI (0.50) | HTTSMN1; SMN2 | |
| SCHEMBL8183516 | 0.84 | ALDH1A1 (0.43) | CNR2FAAHPOLBHTTALDH1A1 | |
| SCHEMBL8187376 | 0.83 | MGLL (0.44) | POLBALDH1A1KMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6130223-A | Thienopyrimidine with phosphodiesterase V inhibiting effect | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-10-10 | — | — | US | disclosed |