Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 3/20 | 0.57 |
| ▸ | PDE4A | P27815 | 3/20 | 0.54 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.54 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.54 |
| ▸ | RARB | P10826 | 10/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | RARA | P10276 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9647803 | 0.91 | PTPN11 (0.46) | PTPN11PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9149323 | 0.86 | PDE4A (0.54) | PTPN11PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8170024 | 0.86 | PDE4A (0.54) | PTPN11PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8170027 | 0.86 | PDE4A (0.54) | PTPN11PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9651231 | 0.83 | ALDH1A1 (0.58) | PTPN11PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9649846 | 0.83 | THRA (0.46) | PTPN11PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8181774 | 0.82 | PDE4A (0.51) | PTPN11PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7169145 | 0.82 | PDE4A (0.51) | PTPN11PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8176758 | 0.82 | PDE4A (0.51) | PTPN11PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7169538 | 0.82 | PDE4A (0.51) | PTPN11PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0267670-B1 | OPTICALLY ACTIVE LIQUID CRYSTAL COMPOUND HAVING CYANO GROUP | Chisso Corporation (JP) | 1992-12-23 | — | — | EP | disclosed |
| US-4886622-A | Optically active liquid crystal compound having cyano group | CHISSO CORPORATION (JP) | 1989-12-12 | — | — | US | disclosed |
| EP-0267670-A1 | Optically active liquid crystal compound having cyano group | Chisso Corporation (JP) | 1988-05-18 | — | — | EP | disclosed |