Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 5/20 | 0.44 |
| ▸ | DPP4 | P27487 | 5/20 | 0.41 |
| ▸ | FAP | Q12884 | 2/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.41 |
| ▸ | PREP | P48147 | 1/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.41 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.40 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.40 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.40 |
| ▸ | STAT6 | P42226 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7400531 | 0.82 | ELANE (0.47) | — | |
| SCHEMBL4275067 | 0.81 | DPP4 (0.46) | ACEDPP4FAPDPP7PREP | |
| SCHEMBL7351756 | 0.80 | TACR1 (0.52) | — | |
| Bromide SCHEMBL11429498 | 0.72 | ALDH1A1 (0.58) | — | |
| SCHEMBL8316371 | 0.72 | ACE (0.64) | ACEDPP4FAPDPP7PREP | |
| SCHEMBL2031883 | 0.72 | DPP4 (0.58) | ACEDPP4FAPDPP7PREP | |
| SCHEMBL7300736 | 0.72 | DPP4 (0.58) | ACEDPP4FAPDPP7PREP | |
| SCHEMBL22673059 | 0.72 | DPP4 (0.58) | ACEDPP4FAPDPP7PREP | |
| SCHEMBL9164453 | 0.72 | ACE (0.64) | ACEDPP4FAPDPP7PREP | |
| SCHEMBL593691 | 0.72 | ACE (0.64) | ACEDPP4FAPDPP7PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0981630-A1 | POLYPEPTIDES HAVING PROLYL PIPEPTIDYL AMINOPEPTIDASE ACTIVITY AND NUCLEIC ACIDS ENCODING SAME | NOVO NORDISK BIOTECH, INC. (US) | 2000-03-01 | — | — | EP | disclosed |
| WO-1998051803-A1 | POLYPEPTIDES HAVING PROLYL PIPEPTIDYL AMINOPEPTIDASE ACTIVITY AND NUCLEIC ACIDS ENCODING SAME | NOVO NORDISK BIOTECH, INC. (US) | 1998-11-19 | — | — | WO | disclosed |