Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 4/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.47 |
| ▸ | HTR1A | P08908 | 3/20 | 0.47 |
| ▸ | DRD2 | P14416 | 3/20 | 0.47 |
| ▸ | HTR2A | P28223 | 3/20 | 0.47 |
| ▸ | HTR2C | P28335 | 3/20 | 0.47 |
| ▸ | HTR7 | P34969 | 3/20 | 0.47 |
| ▸ | DRD3 | P35462 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SLC27A1 | Q6PCB7 | 2/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.42 |
| ▸ | MLNR | O43193 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3824735 | 0.88 | HTR1A (0.52) | DRD4TMEM97SIGMAR1HTR1ADRD2 | |
| SCHEMBL3825171 | 0.87 | RAB9A (0.53) | DRD4TMEM97SIGMAR1HTR1ADRD2 | |
| SCHEMBL3829698 | 0.87 | DRD2 (0.54) | DRD4TMEM97SIGMAR1HTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL3822406 | 0.87 | RAB9A (0.52) | DRD4TMEM97SIGMAR1HTR1ADRD2 | |
| SCHEMBL3831162 | 0.86 | RAB9A (0.53) | DRD4TMEM97SIGMAR1HTR1ADRD2 | |
| SCHEMBL3826499 | 0.86 | HTR1A (0.46) | DRD4TMEM97SIGMAR1HTR1ADRD2 | |
| SCHEMBL3827024 | 0.85 | RAB9A (0.52) | DRD4TMEM97SIGMAR1HTR1ADRD2 | |
| SCHEMBL3830820 | 0.85 | DRD2 (0.52) | DRD4TMEM97SIGMAR1HTR1ADRD2 | |
| SCHEMBL3828068 | 0.85 | HTR1A (0.45) | DRD4TMEM97SIGMAR1HTR1ADRD2 | |
| SCHEMBL3827019 | 0.84 | HRH3 (0.45) | DRD4TMEM97SIGMAR1HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073936-A1 | CARBOXAMIDE DERIVATIVES AS ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | disclosed |