Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 3/20 | 0.42 |
| ▸ | POR | P16435 | 3/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CES2 | O00748 | 2/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | CES1 | P23141 | 2/20 | 0.34 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3329489 | 0.89 | NQO1 (0.50) | NQO1PORELANETDP1MEN1 | |
| SCHEMBL8260282 | 0.73 | NQO1 (0.52) | NQO1PORELANETDP1MEN1 | |
| SCHEMBL3331249 | 0.71 | NQO1 (0.50) | NQO1PORELANETDP1MEN1 | |
| SCHEMBL25704260 | 0.69 | TDP1 (0.36) | TDP1MEN1KMT2ACES2KDM1A | |
| (3R)-Dunnione SCHEMBL29468606 | 0.68 | NQO1 (0.63) | NQO1PORELANETDP1MEN1 | |
| (3R)-Dunnione SCHEMBL103115 | 0.68 | NQO1 (0.63) | NQO1PORELANETDP1MEN1 | |
| SCHEMBL3330784 | 0.68 | STAT3 (0.43) | TDP1MEN1KMT2ACES2KDM1A | |
| Alpha-Dunnione SCHEMBL940069 | 0.67 | NQO1 (0.56) | NQO1PORELANETDP1MEN1 | |
| SCHEMBL8023976 | 0.65 | MALT1 (0.55) | NQO1PORTDP1MEN1KMT2A | |
| SCHEMBL8192096 | 0.65 | NQO1 (0.43) | NQO1PORELANEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008066299-A1 | PHARMACEUTICAL COMPOSITION FOR THE TREATMENT AND PREVENTION OF DISEASES INVOLVING IMPOTENCE | MAZENCE INC. (KR) | 2008-06-05 | — | — | WO | disclosed |
| WO-2008066296-A1 | PHARMACEUTICAL COMPOSITION CONTAINING PHENANTHRENEQUINONE-BASED COMPOUND FOR INTESTINE DELIVERY SYSTEM | MAZENCE INC. (KR) | 2008-06-05 | — | — | WO | disclosed |