SCHEMBL3329489

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8182473	0.89	NQO1 (0.42)	NQO1PORELANETDP1MAPT
	SCHEMBL3331249	0.82	NQO1 (0.50)	NQO1PORELANETDP1MAPT
	(3R)-Dunnione SCHEMBL29468606	0.77	NQO1 (0.63)	NQO1PORELANETDP1MAPT
	(3R)-Dunnione SCHEMBL103115	0.77	NQO1 (0.63)	NQO1PORELANETDP1MAPT
	SCHEMBL6052838	0.73	NQO1 (0.57)	NQO1PORELANETDP1MAPT
	SCHEMBL3330784	0.73	STAT3 (0.43)	TDP1MAPTMEN1KMT2ACES2
	Alpha-Dunnione SCHEMBL940069	0.72	NQO1 (0.56)	NQO1PORELANETDP1MAPT
	(3R)-Dunnione SCHEMBL6052903	0.71	NQO1 (0.56)	NQO1PORELANETDP1MAPT
	SCHEMBL5940500	0.69	NQO1 (0.48)	NQO1PORTDP1MAPTMEN1
	SCHEMBL6052899	0.69	NQO1 (0.67)	NQO1PORELANEMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.