Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7614855 | 0.72 | LMNA (0.49) | LMNAKMT2AMAPK1KDM4EALDH1A1 | |
| SCHEMBL433808 | 0.72 | DYRK1A (0.49) | ACHEMAPTNPC1LMNARAB9A | |
| SCHEMBL17651797 | 0.71 | LMNA (0.40) | ACHEMAPTNPC1LMNARAB9A | |
| SCHEMBL17651767 | 0.71 | LMNA (0.40) | ACHEMAPTNPC1LMNARAB9A | |
| SCHEMBL27838898 | 0.71 | NOTUM (0.52) | MAPTNPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL14080751 | 0.71 | NOTUM (0.52) | MAPTNPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL245938 | 0.71 | MAPT (0.43) | MAPTNPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL8184001 | 0.70 | TOP1 (0.46) | ACHEEPHX1 | |
| SCHEMBL402175 | 0.70 | ACHE (0.59) | ACHEEPHX1ELANE | |
| SCHEMBL31622331 | 0.70 | ACHE (0.59) | ACHEEPHX1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6087493-A | ENZYME IHIBITORS | REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2000-07-11 | — | — | US | disclosed |