SCHEMBL17651797

SCHEMBL17651797

CC(=O)Oc1cccc(C2=C3C=CC(=N3)C(c3c(F)c(F)c(F)c(F)c3F)=C3C=CC(=N3)C(c3cccc(OC(C)=O)c3)=C3C=CC(=N3)C(c3c(F)c(F)c(F)c(F)c3F)=C3C=CC2=N3)c1

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 3/20 0.40
▸ CYP3A4 P08684 1/20 0.40
▸ ADORA2A P29274 1/20 0.38
▸ PTGS2 P35354 1/20 0.38
▸ MAPT P10636 2/20 0.38
▸ ALDH1A1 P00352 2/20 0.38
▸ ACHE P22303 1/20 0.37
▸ GAPDH P04406 2/20 0.37
▸ MEN1 O00255 1/20 0.36
▸ KMT2A Q03164 1/20 0.36
▸ TDP1 Q9NUW8 1/20 0.35
▸ MAOB P27338 1/20 0.35
▸ GAA P10253 1/20 0.34
▸ BACE1 P56817 1/20 0.34
▸ NPC1 O15118 1/20 0.34
▸ TP53 P04637 1/20 0.34
▸ HTT P42858 1/20 0.34
▸ RAB9A P51151 1/20 0.34
▸ SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17651767 1.00 LMNA (0.40) LMNACYP3A4ADORA2APTGS2MAPT
SCHEMBL17651814 0.77 HSD17B1 (0.38) CYP3A4
SCHEMBL17651780 0.77 HSD17B1 (0.38) CYP3A4
SCHEMBL19718155 0.77 PPARA (0.47) —
SCHEMBL10523969 0.74 HSD17B10 (0.47) LMNACYP3A4PTGS2MAPTALDH1A1
SCHEMBL433808 0.72 DYRK1A (0.49) LMNACYP3A4MAPTACHEKMT2A
SCHEMBL8184002 0.71 ACHE (0.42) LMNACYP3A4MAPTALDH1A1ACHE
SCHEMBL18917433 0.71 LMNA (0.36) LMNACYP3A4ADORA2APTGS2MAPT
SCHEMBL7614855 0.70 LMNA (0.49) LMNACYP3A4ALDH1A1MEN1KMT2A
SCHEMBL8908198 0.69 MTNR1A (0.37) LMNACYP3A4MAPTALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12403127-B2 Specifically meso-substituted porphyrins and chlorins for photodynamic therapy BIOLITEC UNTERNEHMENSBETEILIGUNGS II AG (AT) 2025-09-02 — — US disclosed
EP-3201201-B1 SPECIFICALLY MESO-SUBSTITUTED PORPHYRINS AND CHLORINS FOR PHOTODYNAMIC THERAPY BIOLITEC UNTERNEHMENSBETEILIGUNGS II AG (AT) 2022-01-26 — — EP disclosed
US-10456375-B2 Specifically meso-substituted porphyrins and chlorins for photodynamic therapy BIOLITEC UNTERNEHMENSBETEILIGUNGS II AG (AT) 2019-10-29 — — US disclosed
US-20180036284-A1 SPECIFICALLY meso-SUBSTITUTED PORPHYRINS AND CHLORINS FOR PHOTODYNAMIC THERAPY BIOLITEC UNTERNEHMENSBETEILIGUNGS II AG (AT) 2018-02-08 — — US disclosed
EP-3201201-A1 SPECIFICALLY MESO-SUBSTITUTED PORPHYRINS AND CHLORINS FOR PHOTODYNAMIC THERAPY biolitec unternehmensbeteiligungs II AG (AT) 2017-08-09 — — EP disclosed
WO-2016051361-A1 SPECIFICALLY MESO-SUBSTITUTED PORPHYRINS AND CHLORINS FOR PHOTODYNAMIC THERAPY BIOLITEC UNTERNEHMENSBETEILIGUNGS II AG (AT) 2016-04-07 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180036284-A1 SPECIFICALLY meso-SUBSTITUTED PORPHYRINS AND CHLORINS FOR PHOTODYNAMIC THERAPY DHPS, DDT, PPOX LMNA 3830/4885CYP3A4 2334/4885ADORA2A 3453/4885
US-12403127-B2 Specifically meso-substituted porphyrins and chlorins for photodynamic therapy DHPS, DDT, PPOX LMNA 3830/4885CYP3A4 2334/4885ADORA2A 3453/4885
US-10456375-B2 Specifically meso-substituted porphyrins and chlorins for photodynamic therapy DHPS, DDT, PPOX LMNA 3830/4885CYP3A4 2334/4885ADORA2A 3453/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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