Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HHAT | Q5VTY9 | 2/20 | 0.44 |
| ▸ | LHCGR | P22888 | 5/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7880517 | 0.88 | MAPK1 (0.53) | HHATLHCGRNPSR1MAPK1 | |
| SCHEMBL7880312 | 0.82 | HHAT (0.63) | HHATLHCGRNPSR1MAPK1 | |
| SCHEMBL7889696 | 0.82 | HHAT (0.63) | HHATLHCGRNPSR1MAPK1 | |
| SCHEMBL7888339 | 0.81 | MAPK1 (0.60) | HHATLHCGRNPSR1MAPK1LMNA | |
| SCHEMBL8226033 | 0.79 | LHCGR (0.59) | HHATLHCGRNPSR1MAPK1LMNA | |
| SCHEMBL7887663 | 0.77 | CA12 (0.48) | HHATLHCGRNPSR1MAPK1ALDH1A1 | |
| SCHEMBL7885990 | 0.77 | NPSR1 (0.51) | HHATLHCGRNPSR1MAPK1ALDH1A1 | |
| SCHEMBL7880254 | 0.75 | ALDH1A1 (0.60) | HHATLHCGRNPSR1MAPK1ALDH1A1 | |
| SCHEMBL7885827 | 0.75 | LHCGR (0.67) | HHATLHCGRNPSR1MAPK1 | |
| SCHEMBL7891897 | 0.73 | LHCGR (0.59) | HHATLHCGRNPSR1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973778-A1 | 4,5,6,7-TETRAHYDRO-THIENO 3,2-c]PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998040385-A1 | 4,5,6,7-TETRAHYDRO-THIENO[3,2-c]PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1998-09-17 | — | — | WO | disclosed |