Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | RAF1 | P04049 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9035419 | 0.83 | ACHE (0.46) | ACHEMEN1KMT2AL3MBTL1RAF1 | |
| SCHEMBL7666411 | 0.82 | MAPK1 (0.42) | ACHEMEN1KMT2AL3MBTL1RAF1 | |
| SCHEMBL5399245 | 0.80 | MEN1 (0.50) | MEN1KMT2AL3MBTL1RAF1MAPK1 | |
| SCHEMBL8221443 | 0.79 | MEN1 (0.44) | ACHEMEN1KMT2AL3MBTL1RAF1 | |
| SCHEMBL9036456 | 0.78 | ACHE (0.42) | ACHEMEN1KMT2AL3MBTL1MAPK1 | |
| SCHEMBL3722673 | 0.77 | MEN1 (0.47) | MEN1KMT2AL3MBTL1RAF1MAPK1 | |
| SCHEMBL2278697 | 0.77 | MEN1 (0.70) | MEN1KMT2AL3MBTL1RAF1MAPK1 | |
| SCHEMBL7218785 | 0.76 | ACHE (0.48) | ACHEHTR2AHTR2CHTR2BALDH1A1 | |
| Hydrochloric Acid SCHEMBL4866638 | 0.75 | ACHE (0.47) | ACHEHTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL29948190 | 0.74 | ALDH1A1 (0.49) | MEN1KMT2ARAF1MAPK1MAP2K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000021949-A1 | QUINOLONES AS T-RNA SYNTHETASE INHIBITORS AND ANTIBACTERIAL AGENTS | SMITHKLINE BEECHAM PLC (GB) | 2000-04-20 | — | — | WO | disclosed |