Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 5/20 | 0.42 |
| ▸ | LOX | P28300 | 1/20 | 0.41 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | DAO | P14920 | 2/20 | 0.34 |
| ▸ | RRM2 | P31350 | 1/20 | 0.33 |
| ▸ | TKT | P29401 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29404783 | 0.84 | LOXL2 (0.53) | LOXL2LOXCA1CA2CA12 | |
| SCHEMBL619597 | 0.84 | PSIP1 (0.39) | LOXL2LOXPSIP1CA1CA2 | |
| SCHEMBL40545 | 0.84 | LOXL2 (0.53) | LOXL2LOXCA1CA2CA12 | |
| SCHEMBL12266677 | 0.82 | KDM4E (0.41) | CA2TRPV4MAOBDAOTKT | |
| Hydrochloric Acid SCHEMBL3494124 | 0.82 | LOXL2 (0.55) | LOXL2LOXCA1CA2CA12 | |
| SCHEMBL1743280 | 0.81 | TKT (0.39) | CA1CA2CA12CA4CA6 | |
| SCHEMBL8927734 | 0.81 | TRPV4 (0.35) | TRPV4MAOBDAOTKTGPBAR1 | |
| SCHEMBL14552496 | 0.81 | ESR1 (0.41) | TRPV4MAOBDAOTKTGPBAR1 | |
| SCHEMBL27975333 | 0.81 | TRPV4 (0.35) | TRPV4MAOBDAOTKTGPBAR1 | |
| SCHEMBL21503619 | 0.81 | KCNH2 (0.38) | LOXL2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008063670-A1 | HETEROBICYCLIC MATRIX METALLOPROTEASE INHIBITORS | ALANTOS PHARMACEUTICALS HOLDING, INC. (US) | 2008-05-29 | — | — | WO | disclosed |