Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 9/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8345582 | 1.00 | MEN1 (0.47) | MEN1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7845703 | 0.82 | ALDH1A1 (0.48) | MEN1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8350180 | 0.82 | ALDH1A1 (0.48) | MEN1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8349813 | 0.82 | ALDH1A1 (0.46) | MEN1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8349817 | 0.82 | ALDH1A1 (0.46) | MEN1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8003610 | 0.81 | NFE2L2 (0.48) | MEN1CYP1A2MAPTKMT2ANFE2L2 | |
| SCHEMBL8003614 | 0.81 | NFE2L2 (0.48) | MEN1CYP1A2MAPTKMT2ANFE2L2 | |
| SCHEMBL8190644 | 0.79 | CYP1A2 (0.44) | MEN1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8190647 | 0.79 | CYP1A2 (0.44) | MEN1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL9068728 | 0.78 | LMNA (0.44) | MEN1ALDH1A1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5942506-A | TREATMENT OF NERVOUS SYSTEM DISORDERS, ANXIETY | GIS GYOGYSZERGYAR RT. (HU) | 1999-08-24 | — | — | US | disclosed |