Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.40 |
| ▸ | TNKS | O95271 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 5/20 | 0.39 |
| ▸ | CNR2 | P34972 | 4/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.37 |
| ▸ | COMT | P21964 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8179014 | 0.88 | HSD11B1 (0.45) | HSD11B1ALDH1A1TNKSCOMTHSD17B10 | |
| SCHEMBL8178803 | 0.81 | COMT (0.34) | ALDH1A1COMTKDM4E | |
| SCHEMBL8187079 | 0.81 | COMT (0.41) | ALDH1A1L3MBTL1COMT | |
| SCHEMBL8192289 | 0.79 | HSP90AA1 (0.36) | ALDH1A1COMTHSD17B10 | |
| SCHEMBL8177447 | 0.78 | AKR1B1 (0.37) | HSD11B1ALDH1A1KDM4EHPGD | |
| SCHEMBL8188251 | 0.77 | MAPK14 (0.43) | ALDH1A1HSD17B10 | |
| SCHEMBL8177457 | 0.76 | ALDH1A1 (0.33) | HSD11B1ALDH1A1COMTKDM4E | |
| SCHEMBL8186323 | 0.75 | PPOX (0.38) | CNR1L3MBTL1 | |
| SCHEMBL8192247 | 0.74 | PPOX (0.36) | ALDH1A1COMT | |
| SCHEMBL8189134 | 0.73 | TDP1 (0.35) | HSD11B1ALDH1A1COMTKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6015774-A | Pyrazin-2-one derivatives, their use, and intermediates for their production | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-01-18 | — | — | US | disclosed |