Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22771214 | 0.91 | TLR8 (0.60) | TLR8TLR7 | |
| SCHEMBL7508446 | 0.85 | TLR8 (0.62) | TLR8TLR7 | |
| SCHEMBL22790540 | 0.85 | TLR8 (0.72) | TLR8TLR7 | |
| SCHEMBL3032882 | 0.84 | TLR8 (0.61) | TLR8TLR7 | |
| SCHEMBL15496646 | 0.84 | TLR8 (0.56) | TLR8TLR7 | |
| SCHEMBL22771140 | 0.84 | TLR8 (0.72) | TLR8TLR7 | |
| SCHEMBL7505631 | 0.84 | TLR8 (0.63) | TLR8TLR7 | |
| SCHEMBL8179545 | 0.83 | TLR8 (0.60) | TLR8TLR7 | |
| SCHEMBL233010 | 0.83 | TLR8 (0.66) | TLR8TLR7 | |
| SCHEMBL22783803 | 0.82 | TLR8 (0.69) | TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825186-A1 | 2-Aminobenzazepine derivatives and their use for the treatment of immunosuppression | PFIZER INC. (US) | 1998-02-25 | — | — | EP | claimed |
| US-6043238-A | 2-Aminobenzazapine derivatives | PFIZER INC. (US) | 2000-03-28 | — | — | US | disclosed |
| EP-0825186-A1 | 2-Aminobenzazepine derivatives and their use for the treatment of immunosuppression | PFIZER INC. (US) | 1998-02-25 | — | — | EP | disclosed |