Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 20/20 | 0.61 |
| ▸ | TLR7 | Q9NYK1 | 8/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10325225 | 0.90 | TLR8 (0.53) | TLR8TLR7 | |
| SCHEMBL19398238 | 0.89 | TLR8 (0.49) | TLR8TLR7 | |
| SCHEMBL7508446 | 0.86 | TLR8 (0.62) | TLR8TLR7 | |
| SCHEMBL7505631 | 0.85 | TLR8 (0.63) | TLR8TLR7 | |
| SCHEMBL8191084 | 0.84 | TLR8 (0.60) | TLR8TLR7 | |
| SCHEMBL22771214 | 0.84 | TLR8 (0.60) | TLR8TLR7 | |
| SCHEMBL8179545 | 0.84 | TLR8 (0.60) | TLR8TLR7 | |
| SCHEMBL18772071 | 0.84 | TLR8 (0.46) | TLR8TLR7 | |
| SCHEMBL22771262 | 0.83 | TLR8 (0.59) | TLR8TLR7 | |
| SCHEMBL25687947 | 0.83 | TLR8 (0.44) | TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2940009-A1 | METHODS OF SYNTHESIS OF BENZAZEPINE DERIVATIVES | VentiRx Pharmaceuticals, Inc. (US) | 2015-11-04 | — | — | EP | claimed |
| EP-2358683-B1 | METHODS OF SYNTHESIS OF BENZAZEPINE DERIVATIVES | VENTIRX PHARMACEUTICALS INC (US) | 2015-04-01 | — | — | EP | claimed |
| US-8314090-B2 | Methods of synthesis of benzazepine derivatives | VENTIRX PHARMACEUTICALS, INC. (US) | 2012-11-20 | — | — | US | claimed |
| US-20100216989-A1 | METHODS OF SYNTHESIS OF BENZAZEPINE DERIVATIVES | VENTIRX PHARMACEUTICALS, INC. (US) | 2010-08-26 | — | — | US | claimed |
| US-12570610-B2 | Macromolecule-supported aminobenzazepine compounds | BOLT BIOTHERAPEUTICS, INC. (US) | 2026-03-10 | — | — | US | disclosed |
| US-20260034220-A1 | ANTI-CEA IMMUNOCONJUGATES, AND USES THEREOF | BOLT BIOTHERAPEUTICS, INC. (US) | 2026-02-05 | — | — | US | disclosed |
| US-20250263392-A1 | AMINOBENZAZEPINE COMPOUNDS, IMMUNOCONJUGATES, AND USES THEREOF | BOLT BIOTHERAPEUTICS, INC. (US) | 2025-08-21 | — | — | US | disclosed |
| US-20250145575-A1 | MACROMOLECULE-SUPPORTED 8-SULFONYL-BENZAZEPINE COMPOUNDS AND THEIR USES | BOLT BIOTHERAPEUTICS, INC. (US) | 2025-05-08 | — | — | US | disclosed |
| US-20250127914-A1 | ANTIBODY-CONJUGATED 8-SULFONYL-BENZAZEPINE COMPOUNDS AND THEIR USES | BOLT BIOTHERAPEUTICS, INC. (US) | 2025-04-24 | — | — | US | disclosed |
| US-20240299569-A1 | 2-AMINO-4-CARBOXAMIDE-BENZAZEPINE IMMUNOCONJUGATES, AND USES THEREOF | BOLT BIOTHERAPEUTICS, INC. (US) | 2024-09-12 | — | — | US | disclosed |
| CN-117769439-A | 2-amino-4-carboxamide-benzazepine immunoconjugates and uses thereof | 博尔特生物治疗药物有限公司 | 2024-03-26 | — | — | CN | disclosed |
| US-20240091370-A1 | ANTI-HER2 IMMUNOCONJUGATES, AND USES THEREOF | BOLT BIOTHERAPEUTICS, INC. (US) | 2024-03-21 | — | — | US | disclosed |
| US-20110118235-A1 | SUBSTITUTED BENZOAZEPINES AS TOLL-LIKE RECEPTOR MODULATORS | VENTIRX PHARMACEUTICALS, INC. (US) | 2011-05-19 | — | — | US | disclosed |
| US-20110118235-A1 | SUBSTITUTED BENZOAZEPINES AS TOLL-LIKE RECEPTOR MODULATORS | VENTIRX PHARMACEUTICALS, INC. (US) | 2011-05-19 | — | — | US | disclosed |
| US-20110092485-A1 | SUBSTITUTED BENZOAZEPINES AS TOLL-LIKE RECEPTOR MODULATORS | VENTIRX PHARMACEUTICALS, INC. (US) | 2011-04-21 | — | — | US | disclosed |
| US-20110092485-A1 | SUBSTITUTED BENZOAZEPINES AS TOLL-LIKE RECEPTOR MODULATORS | VENTIRX PHARMACEUTICALS, INC. (US) | 2011-04-21 | — | — | US | disclosed |
| WO-2011022509-A2 | SUBSTITUTED BENZOAZEPINES AS TOLL-LIKE RECEPTOR MODULATORS | VENTIRX PHARMACEUTICALS, INC. (US) | 2011-02-24 | — | — | WO | disclosed |
| WO-2011022508-A2 | SUBSTITUTED BENZOAZEPINES AS TOLL-LIKE RECEPTOR MODULATORS | VENTIRX PHARMACEUTICALS, INC. (US) | 2011-02-24 | — | — | WO | disclosed |
| US-20100216989-A1 | METHODS OF SYNTHESIS OF BENZAZEPINE DERIVATIVES | VENTIRX PHARMACEUTICALS, INC. (US) | 2010-08-26 | — | — | US | disclosed |
| US-20100216989-A1 | METHODS OF SYNTHESIS OF BENZAZEPINE DERIVATIVES | VENTIRX PHARMACEUTICALS, INC. (US) | 2010-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250263392-A1 | AMINOBENZAZEPINE COMPOUNDS, IMMUNOCONJUGATES, AND USES THEREOF | IDO2, IDO1, BCR | TLR8 3275/4885TLR7 1547/4885 |
| US-20100216989-A1 | METHODS OF SYNTHESIS OF BENZAZEPINE DERIVATIVES | MAOB, GABBR1, HNMT | TLR8 4758/4885TLR7 4486/4885 |
| US-20240091370-A1 | ANTI-HER2 IMMUNOCONJUGATES, AND USES THEREOF | ERBB2, LTB4R2, PTGER2 | TLR8 114/4885TLR7 752/4885 |
| US-20250145575-A1 | MACROMOLECULE-SUPPORTED 8-SULFONYL-BENZAZEPINE COMPOUNDS AND THEIR USES | BRD4, MUS81, ABCC8 | TLR8 1341/4885TLR7 3140/4885 |
| US-20110118235-A1 | SUBSTITUTED BENZOAZEPINES AS TOLL-LIKE RECEPTOR MODULATORS | TLR8, TLR1, TLR7 | TLR8 1/4885TLR7 3/4885 |
| US-20260034220-A1 | ANTI-CEA IMMUNOCONJUGATES, AND USES THEREOF | IL2, CD47, EPCAM | TLR8 267/4885TLR7 878/4885 |
| US-20110092485-A1 | SUBSTITUTED BENZOAZEPINES AS TOLL-LIKE RECEPTOR MODULATORS | TLR8, TLR1, TLR7 | TLR8 1/4885TLR7 3/4885 |
| US-20250127914-A1 | ANTIBODY-CONJUGATED 8-SULFONYL-BENZAZEPINE COMPOUNDS AND THEIR USES | BCR, CD22, IGSF11 | TLR8 851/4885TLR7 786/4885 |
| US-20240299569-A1 | 2-AMINO-4-CARBOXAMIDE-BENZAZEPINE IMMUNOCONJUGATES, AND USES THEREOF | AADAC, BRD4, IDO2 | TLR8 3049/4885TLR7 1714/4885 |
| US-12570610-B2 | Macromolecule-supported aminobenzazepine compounds | BCL6, CLTB, MET | TLR8 2517/4885TLR7 3346/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.